Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ATM98_RS01495 Genome accession   NZ_CP013651
Coordinates   287105..288478 (+) Length   457 a.a.
NCBI ID   WP_061563822.1    Uniprot ID   A0A127TRC1
Organism   Streptococcus sp. A12     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 282105..293478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS01475 (ATM98_01475) - 282388..284931 (+) 2544 WP_061563819.1 M1 family metallopeptidase -
  ATM98_RS01480 (ATM98_01480) - 284986..285528 (-) 543 WP_061563820.1 biotin transporter BioY -
  ATM98_RS01485 (ATM98_01485) - 285738..286328 (+) 591 WP_061563821.1 hypothetical protein -
  ATM98_RS01490 (ATM98_01490) ciaR 286441..287115 (+) 675 WP_006596563.1 response regulator transcription factor Regulator
  ATM98_RS01495 (ATM98_01495) ciaH 287105..288478 (+) 1374 WP_061563822.1 HAMP domain-containing sensor histidine kinase Regulator
  ATM98_RS01500 (ATM98_01500) - 288727..289113 (+) 387 WP_023022851.1 VOC family protein -
  ATM98_RS01505 (ATM98_01505) - 289329..290693 (+) 1365 WP_237367531.1 polysaccharide deacetylase family protein -
  ATM98_RS01510 (ATM98_01510) - 290726..291814 (-) 1089 WP_061563824.1 DEAD/DEAH box helicase -
  ATM98_RS01515 (ATM98_01515) - 291816..292793 (-) 978 WP_061563825.1 Gfo/Idh/MocA family oxidoreductase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 52524.90 Da        Isoelectric Point: 6.8841

>NTDB_id=163396 ATM98_RS01495 WP_061563822.1 287105..288478(+) (ciaH) [Streptococcus sp. A12]
MLNKIKKTVNADDFSYFIRYFGLFTLIFSTMTLIIIQVMRSSLYTTVDENLKMLSKDRYSIISLANRTGNGMGRDEPDDD
RPEDDEPGPEDGPRPSVTSNSTAILLNDNFENVTTDNGFLDLKTVTFSRSYLNKIKQIQITNHYKQKESYRAYLVDIDPY
DYIDGVKYAVIMTNISQLEQTSEKHESQIALVMICFWGISLFASIFLAKMSVKPLLESMNRQKAFVENASHELRTPLAVL
QNRLETLFRKPEATIMESSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPEFCEIPPSFFDQTFANYEIIAEENDKIFE
YENHVERSLVSDKVLLKQLMTILYDNALKYTEEEGKIRFVAQFKDRYLYLRVEDNGSGIADEDKKRIFDRFYRVDKARTR
QKGGFGLGLSLAKQIVEAFNGTITVRDNKPKGAIFEVKLATKSDSKKKSSSKSMKNK

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=163396 ATM98_RS01495 WP_061563822.1 287105..288478(+) (ciaH) [Streptococcus sp. A12]
ATGCTCAATAAAATTAAAAAAACTGTTAATGCGGATGACTTTTCTTATTTCATCCGCTATTTCGGACTATTTACCTTAAT
TTTCTCGACCATGACCTTGATTATTATTCAAGTGATGCGGTCAAGTCTGTATACAACGGTTGATGAAAATTTAAAGATGC
TGAGTAAAGATCGTTATTCTATTATTAGCTTGGCCAATCGTACAGGAAATGGGATGGGAAGAGACGAACCAGATGATGAC
CGACCAGAAGATGATGAGCCTGGTCCTGAGGATGGCCCTAGACCATCGGTCACTTCCAATAGTACAGCCATCCTCTTGAA
TGATAATTTTGAAAATGTAACGACGGACAATGGTTTCCTAGATCTAAAAACAGTGACCTTTAGTCGCAGCTATTTAAACA
AGATCAAGCAGATTCAAATTACCAACCACTATAAGCAGAAGGAAAGCTATCGCGCTTATTTGGTGGATATTGATCCCTAT
GATTATATTGATGGGGTGAAATATGCCGTGATTATGACCAATATCAGCCAGTTGGAGCAGACCAGTGAAAAACACGAGAG
CCAAATCGCCTTGGTCATGATTTGCTTCTGGGGTATTTCCCTCTTTGCAAGTATCTTCCTGGCTAAAATGAGTGTGAAAC
CTCTCTTAGAGAGCATGAATCGGCAGAAGGCTTTTGTTGAAAATGCTTCTCATGAATTGCGGACACCTTTAGCCGTTTTG
CAAAATCGTTTGGAAACCCTGTTCCGAAAACCAGAGGCAACGATCATGGAATCCAGTGAGAACATCGCCTCCTCTTTGGA
TGAGGTTCGCAATATGCGCTTACTGACGACCAATCTCTTAAACTTAGCCCGTCGAGATGATGGGATTAAACCTGAGTTTT
GTGAAATCCCTCCCTCTTTTTTCGATCAAACCTTTGCCAATTATGAAATCATTGCTGAGGAAAATGATAAAATCTTCGAG
TATGAGAATCATGTCGAAAGGAGTCTGGTGTCTGACAAGGTCCTACTGAAACAGCTGATGACCATTTTGTATGACAATGC
CCTCAAATACACAGAGGAAGAAGGAAAGATACGGTTTGTCGCCCAATTCAAGGATCGCTATCTCTATCTCCGGGTAGAGG
ATAATGGATCAGGGATTGCAGACGAAGATAAAAAGCGGATATTTGATCGATTCTACCGAGTGGATAAGGCGCGGACGCGT
CAAAAGGGTGGTTTTGGGTTAGGACTGTCCTTAGCCAAGCAAATCGTAGAAGCCTTTAATGGTACCATTACTGTTCGAGA
TAACAAGCCTAAAGGTGCTATTTTTGAAGTGAAACTAGCAACCAAGTCAGATAGTAAAAAGAAATCCAGTTCTAAATCAA
TGAAGAACAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A127TRC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae D39

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae R6

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae TIGR4

60.802

98.249

0.597
  ciaH Streptococcus mutans UA159

50.569

96.061

0.486

Multiple sequence alignment