Detailed information NTG0160708

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HSISS4_RS05385
• Genome accession: NZ_CP013216
• Coordinates: 1132268..1133107 (-)
• Length: 279 a.a.
• NCBI ID: WP_059749176.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain HSISS4
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1127268..1138107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSISS4_RS05365 (HSISS4_01037)	-	1127728..1128378 (-)	651	WP_021144082.1	membrane protein	-
HSISS4_RS05370 (HSISS4_01038)	-	1128365..1129093 (-)	729	WP_021144081.1	Lantibiotic transport permease	-
HSISS4_RS05375 (HSISS4_01039)	-	1129098..1129772 (-)	675	WP_021144080.1	ATP-binding cassette domain-containing protein	-
HSISS4_RS05380 (HSISS4_01040)	topA	1129956..1132100 (-)	2145	WP_021144079.1	type I DNA topoisomerase	-
HSISS4_RS05385 (HSISS4_01041)	dprA	1132268..1133107 (-)	840	WP_059749176.1	DNA-processing protein DprA	Machinery gene
HSISS4_RS05390 (HSISS4_01042)	-	1133174..1134094 (-)	921	WP_021144076.1	ROK family protein	-
HSISS4_RS05395 (HSISS4_01043)	-	1134101..1134871 (-)	771	WP_021144075.1	ribonuclease HII	-
HSISS4_RS05400 (HSISS4_01044)	ylqF	1134858..1135712 (-)	855	WP_021144074.1	ribosome biogenesis GTPase YlqF	-
HSISS4_RS05405 (HSISS4_01045)	-	1135841..1136530 (-)	690	WP_021144073.1	XRE family transcriptional regulator	-
HSISS4_RS05410 (HSISS4_01046)	-	1136625..1137140 (-)	516	WP_021144072.1	transcription repressor NadR	-
HSISS4_RS05415 (HSISS4_01047)	-	1137163..1137690 (-)	528	WP_002883896.1	ECF transporter S component	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31277.21 Da
• Isoelectric Point: 8.6599

>NTDB_id=160708 HSISS4_RS05385 WP_059749176.1 1132268..1133107(-) (dprA) [Streptococcus salivarius strain HSISS4]
MNNFELFKLKAAGLTNLNILNILDYQKTQDRKLSLRDMAVVSKSKNAVLFMEKYKSLDIKQLKEQFDRFPTLSIFDKEYP
IELKHAYNPPVLLYYQGNLDLLSKPKLAVVGARKCSETGKQSVRKIVSELGNHFTIVSGLARGIDTCAHMEALKNRGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS

Nucleotide

• Length: 840 bp

>NTDB_id=160708 HSISS4_RS05385 WP_059749176.1 1132268..1133107(-) (dprA) [Streptococcus salivarius strain HSISS4]
ATGAATAATTTTGAACTTTTTAAACTTAAAGCCGCTGGGTTGACGAATTTGAATATCTTAAATATTTTGGACTATCAAAA
GACTCAAGATAGAAAATTGAGTTTACGTGATATGGCAGTGGTATCCAAGTCTAAAAATGCCGTTCTTTTTATGGAAAAGT
ATAAGAGTTTAGATATTAAGCAACTCAAAGAACAATTCGACCGTTTTCCTACGTTATCGATTTTTGATAAAGAATATCCC
ATTGAGCTGAAGCATGCCTATAATCCTCCTGTTCTCCTTTATTATCAGGGGAATCTTGATTTACTGAGTAAACCAAAGCT
AGCAGTTGTTGGGGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGCAAAATTGTTAGTGAACTTGGTAATCACT
TTACTATTGTGAGTGGATTGGCGCGTGGGATTGATACTTGTGCGCATATGGAGGCCTTGAAAAATAGGGGGAACACCATT
GCAGTTATCGGGACTGGACTTGATGTTTATTATCCTAAAGAAAATAAAGCTTTGCAGGACTATATGGCTAAAAATCATTT
AGTTCTTACTGAATATGGACCGGGTGAACAACCTCTCAAGTACCACTTTCCTGAACGCAATCGGATTATTTCTGGATTGT
GTCAAGGAGTTATGGTCGTAGAAGCAAAACTTCGCTCGGGAAGTCTGATTACTTGTGAGCGTGCCATGGAAGAAGGAAGA
GATGTCTTTGCTATTCCAGGAAATATTTTAGATGGAAAGTCAGACGGATGCCATCATTTGATTCAAGAGGGCGCAAAGTG
CATTACGACAGGGTTTGACATCCTTTCAGAGTTTTCTTGA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.043	100	0.72
dprA/cilB/dalA	Streptococcus mitis SK321	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.95	99.642	0.627
dprA	Lactococcus lactis subsp. cremoris KW2	59.353	99.642	0.591
dprA	Latilactobacillus sakei subsp. sakei 23K	40.541	92.832	0.376
dprA	Staphylococcus aureus N315	41.296	88.53	0.366