Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BB405_RS14040 Genome accession   NZ_CP016546
Coordinates   2820674..2821306 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain O177:H21     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2815674..2826306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BB405_RS14015 (BB405_14015) yhfG 2815806..2815973 (+) 168 WP_000736860.1 YhfG family protein -
  BB405_RS14020 (BB405_14020) fic 2815963..2816565 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  BB405_RS14025 (BB405_14025) pabA 2816597..2817160 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  BB405_RS14030 (BB405_14030) argD 2817246..2818466 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BB405_RS14035 (BB405_14035) yhfK 2818533..2820623 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  BB405_RS14040 (BB405_14040) crp 2820674..2821306 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BB405_RS14050 (BB405_14050) yhfA 2821608..2822012 (+) 405 WP_001148908.1 OsmC family protein -
  BB405_RS14055 (BB405_14055) prkB 2822067..2822936 (-) 870 WP_001274680.1 phosphoribulokinase -
  BB405_RS14060 (BB405_14060) yheU 2822990..2823208 (-) 219 WP_000907085.1 YheU family protein -
  BB405_RS14065 (BB405_14065) yheT 2823202..2824224 (-) 1023 WP_000057379.1 hydrolase -
  BB405_RS14070 (BB405_14070) yheS 2824224..2826137 (-) 1914 WP_065749782.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=160625 BB405_RS14040 WP_000242755.1 2820674..2821306(-) (crp) [Escherichia coli strain O177:H21]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=160625 BB405_RS14040 WP_000242755.1 2820674..2821306(-) (crp) [Escherichia coli strain O177:H21]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment