Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SanJ4211_RS04390 Genome accession   NZ_CP012805
Coordinates   870834..871538 (+) Length   234 a.a.
NCBI ID   WP_003024731.1    Uniprot ID   A0AAP6BPY6
Organism   Streptococcus anginosus strain J4211     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 869352..870703 870834..871538 flank 131


Gene organization within MGE regions


Location: 869352..871538
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS04390 (SanJ4211_0861) comEA/celA/cilE 870834..871538 (+) 705 WP_003024731.1 helix-hairpin-helix domain-containing protein Machinery gene

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 24996.90 Da        Isoelectric Point: 4.6812

>NTDB_id=157705 SanJ4211_RS04390 WP_003024731.1 870834..871538(+) (comEA/celA/cilE) [Streptococcus anginosus strain J4211]
MLETIIEKMKEYKILIGLSLIGLIIAGFFMINGQSSRQSNVAELAQETVTSSEAESEEISTGTKKNSQKEKAEPQTSSSE
ESEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVVYVATMGENAASVSSNTGQSSTS
GTSEVASQKGNKVNLNTADLSELQTISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=157705 SanJ4211_RS04390 WP_003024731.1 870834..871538(+) (comEA/celA/cilE) [Streptococcus anginosus strain J4211]
ATGTTAGAGACAATCATTGAAAAGATGAAAGAGTATAAAATTTTGATTGGTTTAAGTTTGATTGGTTTGATAATAGCAGG
ATTTTTTATGATAAATGGTCAATCTAGTAGACAATCAAATGTAGCAGAGCTCGCACAGGAAACAGTTACGAGTTCGGAGG
CAGAATCAGAAGAAATTTCAACTGGAACGAAGAAAAACTCACAGAAAGAAAAAGCAGAGCCTCAAACGAGTTCCAGTGAA
GAATCAGAATTTTTAACCGTAGATGTCAAGGGTGCAGTCAAAAATCCAGGTATTTATCAACTGAAAAAGACTAGCCGTAT
CAATGATGCGATTCAAAAAGCAGGTGGTTTAACGACAGACGCTGACAGCAAGTCTATCAATTTGGCGCAGAAACTAACGG
ATGAAGCTGTTGTTTATGTGGCAACTATGGGTGAGAATGCGGCGAGTGTTTCAAGCAATACAGGACAATCTTCAACATCA
GGAACTAGTGAAGTCGCATCGCAAAAAGGGAATAAGGTCAATCTAAATACAGCTGATTTATCTGAGTTGCAGACCATTTC
TGGTATTGGTCAAAAACGCGCGCAAGATATTTTAGATTATCGGGAGGCAAACGGGAAATTTAATTCCGTTGATGACCTGA
AAAATGTATCAGGAGTAGGTGCTAAAACACTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae R6

53.219

99.573

0.53
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

53.219

99.573

0.53
  comEA/celA/cilE Streptococcus pneumoniae Rx1

53.219

99.573

0.53
  comEA/celA/cilE Streptococcus pneumoniae D39

53.219

99.573

0.53
  comEA/celA/cilE Streptococcus mitis SK321

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.502

99.573

0.513
  comEA Streptococcus thermophilus LMD-9

44.255

100

0.444
  comEA Lactococcus lactis subsp. cremoris KW2

42.06

99.573

0.419

Multiple sequence alignment