Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SanJ4211_RS03610 Genome accession   NZ_CP012805
Coordinates   719602..720303 (+) Length   233 a.a.
NCBI ID   WP_021001531.1    Uniprot ID   A0A0P0N857
Organism   Streptococcus anginosus strain J4211     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 714602..725303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS03590 (SanJ4211_0691) ccpA 715447..716451 (+) 1005 WP_022526272.1 catabolite control protein A Regulator
  SanJ4211_RS03595 (SanJ4211_0692) - 716631..717629 (+) 999 WP_021001528.1 glycosyltransferase family 4 protein -
  SanJ4211_RS03600 (SanJ4211_0693) - 717631..718944 (+) 1314 WP_057489614.1 glycosyltransferase family 4 protein -
  SanJ4211_RS03605 (SanJ4211_0694) - 718971..719312 (+) 342 WP_021001530.1 hypothetical protein -
  SanJ4211_RS03610 (SanJ4211_0695) micA 719602..720303 (+) 702 WP_021001531.1 response regulator YycF Regulator
  SanJ4211_RS03615 (SanJ4211_0696) micB 720296..721648 (+) 1353 WP_021001532.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SanJ4211_RS03620 (SanJ4211_0697) vicX 721651..722454 (+) 804 WP_021001533.1 MBL fold metallo-hydrolase Regulator
  SanJ4211_RS03625 - 722463..722823 (+) 361 Protein_693 YbaN family protein -
  SanJ4211_RS03630 (SanJ4211_0700) rnc 723205..723903 (+) 699 WP_021001534.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26869.83 Da        Isoelectric Point: 4.6824

>NTDB_id=157701 SanJ4211_RS03610 WP_021001531.1 719602..720303(+) (micA) [Streptococcus anginosus strain J4211]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=157701 SanJ4211_RS03610 WP_021001531.1 719602..720303(+) (micA) [Streptococcus anginosus strain J4211]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCGATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACTGCCTTCGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGATAAAGTCATTGGTCTCGAAATTGGAGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AGATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0P0N857

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.661

100

0.807
  covR Streptococcus salivarius strain HSISS4

44.783

98.712

0.442
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

98.283

0.442
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment