Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SanJ4211_RS03405 Genome accession   NZ_CP012805
Coordinates   677842..678687 (+) Length   281 a.a.
NCBI ID   WP_021001513.1    Uniprot ID   A0AAP6EMK6
Organism   Streptococcus anginosus strain J4211     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 672842..683687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS03375 (SanJ4211_0649) - 673174..674052 (+) 879 WP_003030484.1 F0F1 ATP synthase subunit gamma -
  SanJ4211_RS03380 (SanJ4211_0650) atpD 674087..675493 (+) 1407 WP_003030503.1 F0F1 ATP synthase subunit beta -
  SanJ4211_RS03385 (SanJ4211_0651) - 675504..675923 (+) 420 WP_003025266.1 F0F1 ATP synthase subunit epsilon -
  SanJ4211_RS03390 (SanJ4211_0652) - 676023..676253 (+) 231 WP_041784005.1 DUF1146 family protein -
  SanJ4211_RS03395 (SanJ4211_0653) murA 676292..677572 (+) 1281 WP_021001512.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SanJ4211_RS03400 (SanJ4211_0654) - 677565..677741 (+) 177 WP_041784006.1 DNA-directed RNA polymerase subunit beta -
  SanJ4211_RS03405 (SanJ4211_0655) endA 677842..678687 (+) 846 WP_021001513.1 DNA/RNA non-specific endonuclease Machinery gene
  SanJ4211_RS03410 (SanJ4211_0656) - 678977..680713 (+) 1737 WP_057489610.1 ABC transporter ATP-binding protein -
  SanJ4211_RS03415 (SanJ4211_0657) - 680723..682492 (+) 1770 WP_057489611.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30911.57 Da        Isoelectric Point: 10.2583

>NTDB_id=157699 SanJ4211_RS03405 WP_021001513.1 677842..678687(+) (endA) [Streptococcus anginosus strain J4211]
MARKKSNQKVAQSVVGVFLALVLALGGYSFSNHRTSTSHSDSSAINRSIRMNHAAPSQELAQSVVTESVKRQLEGKIEWN
GSGAFIINENKTTLDAKIASVPYADNKTKLVRGQTVPTVANALLSKATRQYRNREETGNGSTTWTPAGWHQVKHLSGEYH
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANTSYSTGQNFYETKIRKALDKNKRVRYRVTLIYANEQDLV
PVGSHIEGKSNDDNLEINVFVPNVQTGIRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=157699 SanJ4211_RS03405 WP_021001513.1 677842..678687(+) (endA) [Streptococcus anginosus strain J4211]
ATGGCGAGAAAGAAGTCCAACCAGAAAGTAGCGCAAAGTGTAGTAGGCGTATTTCTTGCACTCGTTCTTGCGCTGGGAGG
TTATTCTTTTAGCAATCATCGCACTAGTACGAGTCATTCTGATAGCTCTGCTATTAATCGAAGTATTCGGATGAATCATG
CAGCACCCAGTCAAGAATTAGCACAGAGTGTTGTGACAGAATCCGTTAAACGACAGCTCGAAGGAAAGATCGAATGGAAT
GGATCGGGAGCCTTTATAATCAACGAAAATAAAACAACATTGGATGCCAAAATTGCAAGCGTTCCTTACGCGGATAATAA
GACCAAGCTTGTTCGAGGTCAGACTGTTCCGACTGTAGCTAATGCTCTTTTATCCAAAGCTACTCGTCAGTATAGGAATC
GTGAAGAAACAGGTAATGGTTCAACAACTTGGACACCTGCTGGCTGGCATCAGGTGAAGCATTTATCGGGTGAATATCAT
CATGCAGTTGACCGTGGACATCTGCTAGGTTATGCCTTGATTGGTAACTTGAAAGGCTTTGATGCTTCGACCAGCAACCC
GAAAAACATCGCTGTGCAAACAGCTTGGGCTAATCAAGCCAATACTAGTTATTCTACGGGTCAAAATTTTTATGAAACAA
AGATACGTAAGGCACTAGACAAAAATAAACGAGTTCGGTATCGGGTGACTTTGATTTATGCCAATGAACAGGATTTGGTG
CCGGTTGGTTCGCATATTGAAGGCAAATCTAATGACGACAATCTGGAAATAAATGTCTTTGTCCCCAACGTACAGACAGG
AATTCGATTAAATTATCAGACAGGAGAAGTGACCGTTACCAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(83-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

75.664

80.427

0.609
  endA Streptococcus pneumoniae D39

75.664

80.427

0.609
  endA Streptococcus pneumoniae R6

75.664

80.427

0.609
  endA Streptococcus pneumoniae TIGR4

75.664

80.427

0.609

Multiple sequence alignment