Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   RN86_RS10345 Genome accession   NZ_CP012648
Coordinates   2127640..2128341 (-) Length   233 a.a.
NCBI ID   WP_012000241.1    Uniprot ID   -
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2122640..2133341
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS10325 (RN86_10330) rnc 2124159..2124857 (-) 699 WP_012000242.1 ribonuclease III -
  RN86_RS10330 (RN86_10335) - 2125099..2125455 (-) 357 WP_045773784.1 YbaN family protein -
  RN86_RS10335 (RN86_10340) vicX 2125490..2126293 (-) 804 WP_045502133.1 MBL fold metallo-hydrolase Regulator
  RN86_RS10340 (RN86_10345) micB 2126286..2127647 (-) 1362 WP_053794800.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RN86_RS10345 (RN86_10350) micA 2127640..2128341 (-) 702 WP_012000241.1 response regulator YycF Regulator
  RN86_RS10350 (RN86_10355) thrS 2128550..2130493 (-) 1944 WP_053794801.1 threonine--tRNA ligase -
  RN86_RS11700 (RN86_10360) - 2130599..2130955 (-) 357 WP_053794916.1 hypothetical protein -
  RN86_RS11705 (RN86_10365) - 2131287..2131595 (-) 309 WP_053794802.1 hypothetical protein -
  RN86_RS10365 (RN86_10370) - 2131688..2133001 (-) 1314 WP_045773788.1 glycosyltransferase family 4 protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26817.56 Da        Isoelectric Point: 4.6297

>NTDB_id=156108 RN86_RS10345 WP_012000241.1 2127640..2128341(-) (micA) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQENEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=156108 RN86_RS10345 WP_012000241.1 2127640..2128341(-) (micA) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGAAGAAAATATTAGTTGTAGATGATGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTAGTGACTGCTTTTGATGGCCGTGAAGCTCTTGAGATGTTTGAAGCTGAAAATCCTGATATTTTGATTTTGGATTTGA
TGTTGCCAGAGTTGGACGGGCTAGAAGTAGCACGCACCATTCGAAAGACCAGTAATGTTCCAATTATTGTCCTATCGGCT
AAAGATAGTGAGTTTGATAAAGTTATCGGCCTTGAGATCGGAGCAGACGACTATGTGACCAAGCCTTTCTCTAACCGTGA
ACTTCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCGGAATTTGCTGTAGATACCCAAGAAAATGAAAAGGGCTCAAATG
AGTTGACAGTGGGTGAATTGCAAATTTTACCAGATGCTTTTGTTGCCAAGAAACATGGTGAAGAACTAGAACTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCTAGTCATGTTGGTCAAGTAATGACACGCGAACACCTACTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGACGTGCGCACTGTTGATGTGACGATTCGCCGCCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGTGTTGGCTACTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.12

100

0.841
  vicR Streptococcus mutans UA159

80

100

0.807
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

99.142

0.446
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.5

99.571

0.373

Multiple sequence alignment