Detailed information NTG0156107

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: RN86_RS10340
• Genome accession: NZ_CP012648
• Coordinates: 2126286..2127647 (-)
• Length: 453 a.a.
• NCBI ID: WP_053794800.1
• Uniprot ID: A0AB35FRT7
• Organism: Streptococcus gordonii strain KCOM 1506 (= ChDC B679)
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2121286..2132647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RN86_RS10325 (RN86_10330)	rnc	2124159..2124857 (-)	699	WP_012000242.1	ribonuclease III	-
RN86_RS10330 (RN86_10335)	-	2125099..2125455 (-)	357	WP_045773784.1	YbaN family protein	-
RN86_RS10335 (RN86_10340)	vicX	2125490..2126293 (-)	804	WP_045502133.1	MBL fold metallo-hydrolase	Regulator
RN86_RS10340 (RN86_10345)	micB	2126286..2127647 (-)	1362	WP_053794800.1	cell wall metabolism sensor histidine kinase VicK	Regulator
RN86_RS10345 (RN86_10350)	micA	2127640..2128341 (-)	702	WP_012000241.1	response regulator YycF	Regulator
RN86_RS10350 (RN86_10355)	thrS	2128550..2130493 (-)	1944	WP_053794801.1	threonine--tRNA ligase	-
RN86_RS11700 (RN86_10360)	-	2130599..2130955 (-)	357	WP_053794916.1	hypothetical protein	-
RN86_RS11705 (RN86_10365)	-	2131287..2131595 (-)	309	WP_053794802.1	hypothetical protein	-

Sequence

Protein

• Length: 453 a.a.
• Molecular weight: 51625.69 Da
• Isoelectric Point: 4.3991

>NTDB_id=156107 RN86_RS10340 WP_053794800.1 2126286..2127647(-) (micB) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MIENIRQFVFSVDFVFVLIVLGFILVVALLFLENRRDNRQLRLLNQKIKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VTRLTQENLEQETKRLTSILSYMTDGVLATNRRGQIIMINDMASKQLGVDPEEVQNTSILDLLDIADEYDLRDLITKMPE
LTIDSQDENGEFLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPEFVKVSLTETNRMMRMVSDLLSLSRIDNDSSHLDVELTNFTAFITFILNRFDKIKSQDETKKYEIVRDYPITPIW
VEIDTDKMTQVIDNIMNNAIKYSPDGGKITVGMKTTEDQLIISISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHHGFIWAKSEYEVGSTFTIVLPYDKDAVLDDGWESEEVESKDD

Nucleotide

• Length: 1362 bp

>NTDB_id=156107 RN86_RS10340 WP_053794800.1 2126286..2127647(-) (micB) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGATTGAAAATATTAGACAATTTGTGTTTTCTGTAGATTTTGTTTTTGTTTTAATTGTTTTAGGTTTTATTTTGGTTGT
TGCCCTTCTCTTTTTAGAGAATAGAAGGGATAATCGTCAACTTCGTCTGCTCAATCAAAAGATCAAAGATTTAATCGCAG
GAGACTATTCCGAGGTTCTGGATATGCAGGGCAGTCCAGAAATTACGGATATGACCAATAGTATAAATGATTTGTCTGAG
GTAACTAGATTAACACAAGAAAATCTGGAGCAAGAAACCAAACGTTTGACTAGTATTTTGTCCTACATGACGGATGGGGT
TTTGGCAACCAACCGTAGGGGCCAGATTATCATGATTAATGATATGGCTTCTAAGCAACTAGGTGTTGATCCAGAGGAAG
TCCAAAATACAAGTATTTTAGACTTGTTGGATATTGCGGATGAATATGATCTGCGAGATTTAATTACCAAGATGCCGGAA
TTGACGATTGATTCACAGGATGAAAATGGAGAATTTTTAAGTCTGCGTGTTCGTTTTGCCTTGGTTCGTAGGGAATCCGG
TTTTATCTCTGGTTTGGTAGCTGTTCTGCACGATACGACGGAACAGGAAAAAGAGGAACGGGAACGTCGACTTTTTGTCT
CAAACGTGAGTCATGAGCTCCGTACCCCTTTGACAAGTGTTAAGTCTTACCTAGAAGCTTTGGACGAGGGCGCTCTTTCT
GAGCCAGTTGCTCCCGAATTTGTTAAGGTCTCCCTTACGGAAACAAACCGAATGATGCGGATGGTTTCTGATTTGCTTAG
CTTATCAAGGATTGATAATGATAGCAGCCATTTGGATGTGGAATTAACTAATTTTACAGCCTTTATCACTTTTATTTTGA
ATCGTTTTGATAAAATTAAAAGTCAGGATGAAACCAAAAAATACGAGATTGTGCGCGATTATCCAATCACACCTATATGG
GTTGAAATTGATACTGATAAAATGACGCAGGTCATTGATAATATCATGAATAATGCTATCAAGTATTCTCCAGATGGTGG
AAAGATTACTGTAGGAATGAAAACGACTGAAGATCAGTTGATTATTTCAATTTCTGATGAAGGATTGGGAATTCCTAAGA
AAGACCTGCCTAAGATCTTTGACCGTTTTTATCGAGTAGATAAGGCTCGAAGCCGTGCGCAAGGCGGAACAGGTTTAGGA
CTTGCGATTGCAAAAGAAATCATCAAGCAACACCATGGCTTTATCTGGGCTAAGAGTGAGTATGAAGTCGGATCGACTTT
TACAATTGTCCTGCCGTATGATAAGGATGCTGTTTTGGATGATGGCTGGGAAAGTGAAGAAGTAGAAAGTAAAGATGACT
AA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (96-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	80.594	96.689	0.779
vicK	Streptococcus mutans UA159	70.56	90.728	0.64