Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   RN86_RS03355 Genome accession   NZ_CP012648
Coordinates   685434..686792 (+) Length   452 a.a.
NCBI ID   WP_053794281.1    Uniprot ID   -
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 680434..691792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS03340 (RN86_03335) - 681216..681938 (+) 723 WP_053794279.1 ABC transporter ATP-binding protein -
  RN86_RS03345 (RN86_03340) rpsD 682205..682816 (+) 612 WP_008810013.1 30S ribosomal protein S4 -
  RN86_RS03350 (RN86_03345) comA 683271..685424 (+) 2154 WP_053794280.1 peptide cleavage/export ABC transporter ComA Regulator
  RN86_RS03355 (RN86_03350) comB 685434..686792 (+) 1359 WP_053794281.1 competence pheromone export protein ComB Regulator
  RN86_RS03360 (RN86_03355) lytF 686911..688560 (-) 1650 WP_053794282.1 GBS Bsp-like repeat-containing protein Regulator
  RN86_RS03365 (RN86_03360) purD 688805..690064 (+) 1260 WP_053794283.1 phosphoribosylamine--glycine ligase -
  RN86_RS03370 (RN86_03365) - 690124..691317 (+) 1194 WP_053794284.1 ATP-grasp domain-containing protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 49904.18 Da        Isoelectric Point: 5.5701

>NTDB_id=156062 RN86_RS03355 WP_053794281.1 685434..686792(+) (comB) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MNEQFLESAEFYQKRYHNFASCLIVPSLILLVFLVGFSMLAKKEITISSRASVEASRVLAQIQSTSNQPIIANHLAENKE
VKKGDLLIQYAVEGEGAQEQKFSSQLGLLKDQKEKLETLRSSLESGRNQFTEPDSYGYEQSFKDYQNQVESMTSSVNQQN
ATIASQNAAASQSQAELGGVISDVDSKLNDYRNLKNAIQSGVGIDASHPLYSLYQSYRDQLSLAEDKATAQSQIVAQLDG
QISQLEATAATYRVQYAGAGAQQAYASNLSSQLASLKAQYLVKVGQELTTLTQQILEAESNLKLQETVSKRGQILAEMDG
LLHLNPEVQGSTLVAEGTALAQIYPKITSERKIKIVTYVSSKDVSTIKNGDKVRFITADDANKQMILTSQISSIDANATQ
TKQGNFFKVECEMAVSKDQAKKLRYGLEGKFVMVTGEKTYFSYYMEKFFNLG

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=156062 RN86_RS03355 WP_053794281.1 685434..686792(+) (comB) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGAATGAACAATTTTTAGAAAGTGCAGAGTTTTATCAGAAACGTTATCATAATTTTGCAAGTTGTTTAATTGTGCCAAG
TCTTATTTTACTAGTATTTCTAGTTGGTTTTTCCATGCTGGCTAAAAAAGAAATTACGATTTCTAGTCGTGCTTCTGTAG
AAGCTAGCCGAGTACTAGCTCAGATTCAGTCGACTAGTAACCAGCCTATCATTGCGAATCATTTGGCAGAAAACAAGGAG
GTCAAAAAAGGGGACCTGCTAATCCAGTATGCAGTAGAAGGAGAGGGGGCTCAGGAACAGAAGTTTTCCAGCCAGCTTGG
CTTACTCAAAGATCAAAAAGAAAAACTAGAAACTTTGCGTTCCAGTTTAGAAAGCGGGCGTAATCAATTTACTGAGCCAG
ATAGTTATGGCTACGAACAAAGCTTTAAAGACTACCAGAATCAAGTAGAGAGTATGACTAGTTCTGTGAATCAGCAAAAT
GCTACGATTGCTTCACAAAATGCAGCGGCCAGTCAGTCTCAGGCGGAACTGGGCGGTGTTATCAGTGATGTGGATAGCAA
ACTAAATGACTATCGAAACTTGAAAAATGCCATTCAAAGTGGGGTGGGTATAGATGCATCGCACCCTCTTTACTCCTTGT
ATCAGTCCTATCGTGATCAGTTGAGTTTGGCAGAGGATAAGGCAACAGCTCAAAGTCAGATTGTAGCTCAATTAGATGGG
CAAATCTCTCAATTGGAAGCAACAGCTGCGACTTATCGTGTCCAATATGCTGGTGCAGGCGCCCAACAAGCCTATGCTAG
CAATTTATCCAGTCAGTTGGCTTCACTGAAAGCCCAGTATCTGGTGAAAGTAGGACAAGAATTGACCACTCTGACTCAGC
AAATCTTGGAAGCCGAGAGCAATCTTAAACTTCAAGAAACAGTCTCTAAGCGAGGTCAGATTTTGGCTGAAATGGATGGC
TTGCTTCACTTAAATCCAGAAGTACAAGGATCTACTCTGGTGGCAGAAGGAACTGCTTTGGCTCAGATTTACCCCAAAAT
AACCAGTGAAAGAAAAATCAAAATTGTCACATATGTCTCTTCCAAGGATGTATCTACTATTAAAAATGGAGACAAGGTGC
GCTTTATTACTGCTGATGACGCTAACAAACAAATGATTTTGACATCCCAAATTTCCAGTATTGATGCTAATGCTACCCAA
ACCAAACAGGGAAATTTCTTTAAAGTAGAATGCGAAATGGCTGTTAGTAAAGATCAAGCTAAGAAGCTCCGCTATGGCTT
GGAAGGTAAATTTGTCATGGTAACTGGGGAAAAGACTTATTTCAGCTATTATATGGAGAAGTTTTTTAATCTTGGTTGA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(314-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

98.673

100

0.987
  comB Streptococcus pneumoniae Rx1

56

99.558

0.558
  comB Streptococcus pneumoniae D39

56

99.558

0.558
  comB Streptococcus pneumoniae R6

56

99.558

0.558
  comB Streptococcus mitis NCTC 12261

55.778

99.558

0.555
  comB Streptococcus pneumoniae TIGR4

55.556

99.558

0.553
  comB Streptococcus mitis SK321

55.111

99.558

0.549

Multiple sequence alignment