Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   RN86_RS03350 Genome accession   NZ_CP012648
Coordinates   683271..685424 (+) Length   717 a.a.
NCBI ID   WP_053794280.1    Uniprot ID   -
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 678271..690424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS03325 (RN86_03320) - 679169..679459 (+) 291 WP_053794885.1 thiamine-binding protein -
  RN86_RS03330 (RN86_03325) - 679422..680174 (+) 753 WP_053794278.1 ABC transporter permease -
  RN86_RS03335 (RN86_03330) - 680215..681216 (+) 1002 WP_155465100.1 ABC transporter substrate-binding protein -
  RN86_RS03340 (RN86_03335) - 681216..681938 (+) 723 WP_053794279.1 ABC transporter ATP-binding protein -
  RN86_RS03345 (RN86_03340) rpsD 682205..682816 (+) 612 WP_008810013.1 30S ribosomal protein S4 -
  RN86_RS03350 (RN86_03345) comA 683271..685424 (+) 2154 WP_053794280.1 peptide cleavage/export ABC transporter ComA Regulator
  RN86_RS03355 (RN86_03350) comB 685434..686792 (+) 1359 WP_053794281.1 competence pheromone export protein ComB Regulator
  RN86_RS03360 (RN86_03355) lytF 686911..688560 (-) 1650 WP_053794282.1 GBS Bsp-like repeat-containing protein Regulator
  RN86_RS03365 (RN86_03360) purD 688805..690064 (+) 1260 WP_053794283.1 phosphoribosylamine--glycine ligase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80611.61 Da        Isoelectric Point: 7.0504

>NTDB_id=156061 RN86_RS03350 WP_053794280.1 683271..685424(+) (comA) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MKFRKRHYRAQVDTRDCGVAALAMVFGYYGSYFSLATLREKAKTTNDGTTALGLVKVAEGLNFETRAFKADMGIFDLEDV
SYPFIVHVLKEGKLLHYYVVTGQDKHTIHIADPDSQVKMTKISRERFEQEWTGITIFLAPSPAYKPSQEKKNGLLDFIPL
LIKQKGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEIVSRFTDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYAL
IIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVTYLKKSFAYGRSESLQKVLKAVARL
ILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVQSEFNEEKLIKDLSHF
PADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYGPNQGDICLGGVNLNQLDKQALRQYI
NYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIIDNLMALDKTIIFIAHRLTIAERSEQVVVLDQGRIVESGSHKELIEKEGFYHHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=156061 RN86_RS03350 WP_053794280.1 683271..685424(+) (comA) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGAAATTTAGGAAACGGCATTACAGAGCGCAAGTTGATACTAGGGATTGCGGTGTGGCAGCTCTGGCTATGGTTTTTGG
TTATTATGGATCGTATTTTTCCTTGGCTACACTACGAGAAAAGGCAAAAACGACTAATGATGGCACAACTGCTTTGGGTT
TGGTGAAAGTTGCTGAGGGCTTAAATTTTGAGACAAGGGCTTTTAAAGCTGATATGGGAATCTTTGATCTGGAAGATGTA
TCTTATCCTTTCATCGTTCATGTACTTAAGGAAGGGAAGCTCCTGCATTATTATGTTGTGACGGGCCAAGATAAACACAC
GATTCATATTGCAGACCCAGATTCTCAAGTTAAGATGACAAAGATTTCGCGAGAGCGTTTCGAACAGGAGTGGACAGGGA
TTACCATTTTCCTAGCTCCTAGTCCAGCCTATAAACCTAGTCAGGAAAAGAAAAATGGACTTTTAGACTTCATTCCCTTA
TTGATTAAGCAGAAGGGATTGATTGCTAATATTGTACTTGCAACTTTGCTGGTAACGTTGATCAATATTGTTGGATCCTA
CTACCTTCAATCGATTATTGATACTTATGTGCCTGATCATATGAAAACGACGCTGGGTATGATTTCTATCGGCTTGATTA
TTGTCTACATTTTGCAGCAATTCTTGTCTTATGCCCAAGAATATTTACTCTTGGTTTTGGGGCAACGTCTATCAATTGAT
GTGATCTTATCCTATATCAAGCACGTTTTTCAGCTACCTATGTCATTTTTCGCGACAAGGCGGACAGGGGAAATTGTTTC
TCGTTTTACAGACGCCAATCGGATTATTGATGCCTTGGCCAGTACAATCTTGTCTATTTTCTTGGATGTGTCGATTGTAT
CGATCATTGCGATTGTTCTTTTTTCACAAAATAGCAGTCTTTTCTTTTTGACCTTGCTAGGAATCCCAGTTTACGCTCTC
ATTATTTTTCTTTTTATGAAGCCTTTTGAAAAGATGAATCATGAGACGATGGAAGCAAATAGTCTGTTGTCGTCTTCCAT
TATTGAAGATATCAATGGGATTGAGACGATCAAGTCTTTGACTAGTGAAAAGCAACGTTATCAGAAGATTGACAAGGAAT
TTGTGACTTATCTGAAAAAGTCTTTTGCATATGGACGTTCTGAGAGTTTACAAAAAGTCTTGAAAGCAGTAGCTCGTTTG
ATTTTAAACGTCTTGATTTTATGGCTAGGAGCTACACTTGTCATGGATCAAAAAATCAGTCTTGGTCAGCTCATCACTTA
TAATACACTTCTAGTCTACTTTACTAATCCTTTAGAAAATATTATCAATTTGCAAACGAAATTACAGTCTGCTCGTGTAG
CCAACGAGCGTCTCAATGAGGTCTATTTAGTCCAGTCTGAGTTTAATGAAGAGAAGCTTATTAAAGACTTGAGCCACTTT
CCGGCTGACATCGATTTTCGTGGAGTCAGTTATAAGTATGGCTATGGGGCCAATGTATTATCAGAAATTGACTTGCATAT
TCCTGCTGGAAGTAAGACCAGCTTTGTTGGTGTATCAGGATCAGGAAAAACAACCTTGGCCAAGATGATGGTGCATTTTT
ACGGTCCGAATCAAGGGGATATTTGTCTGGGAGGTGTCAATCTCAATCAGCTGGATAAGCAGGCACTGCGCCAATATATC
AACTATCTTCCCCAGCAACCTTATGTTTTTAATGGAACTATTTTGGAAAATTTACTCTTAGGTGCGCGTGAAGGCACGAC
TCAAGAAGATATTCTGCGGGCGGTAGAATTGGCAGAAATTAGGTCGGATATTGAGCGGATGCCTCTCAATTATCAGACAG
AGCTATCAGCAGATGGAGCAGGGATTTCAGGTGGTCAACGCCAGCGTATTGCTCTAGCGAGGGCTCTCTTGACAGATGCA
CCAGTGCTTATCTTAGATGAAGCAACGAGTAGTCTGGATATTCTAACAGAGAAGCGGATCATTGATAATCTGATGGCGCT
TGATAAGACGATTATTTTCATCGCGCATCGTTTGACTATTGCGGAACGTTCGGAGCAGGTGGTCGTTTTGGATCAAGGTA
GGATTGTTGAGAGTGGAAGTCATAAGGAGCTGATCGAAAAAGAAGGCTTTTACCACCATTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

97.49

100

0.975
  comA Streptococcus mitis NCTC 12261

81.172

100

0.812
  comA Streptococcus pneumoniae Rx1

81.032

100

0.81
  comA Streptococcus pneumoniae D39

81.032

100

0.81
  comA Streptococcus pneumoniae R6

81.032

100

0.81
  comA Streptococcus mitis SK321

80.753

100

0.808
  comA Streptococcus pneumoniae TIGR4

80.614

100

0.806
  comA/nlmT Streptococcus mutans UA159

64.714

100

0.647

Multiple sequence alignment