Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   RN80_RS06060 Genome accession   NZ_CP012646
Coordinates   1235974..1236681 (+) Length   235 a.a.
NCBI ID   WP_049539286.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1230974..1241681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS06035 (RN80_06050) - 1231170..1231841 (+) 672 WP_060628220.1 GTP pyrophosphokinase -
  RN80_RS06040 (RN80_06055) - 1231825..1232643 (+) 819 WP_000799056.1 NAD kinase -
  RN80_RS06045 (RN80_06060) - 1232640..1233536 (+) 897 WP_060628222.1 RluA family pseudouridine synthase -
  RN80_RS06050 (RN80_06065) pta 1233580..1234554 (+) 975 WP_000451580.1 phosphate acetyltransferase -
  RN80_RS06055 (RN80_06070) mutY 1234743..1235918 (+) 1176 WP_060628224.1 A/G-specific adenine glycosylase -
  RN80_RS06060 (RN80_06075) micA 1235974..1236681 (+) 708 WP_049539286.1 response regulator YycF Regulator
  RN80_RS06065 (RN80_06080) micB 1236674..1238023 (+) 1350 WP_060628226.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RN80_RS06070 (RN80_06085) vicX 1238025..1238834 (+) 810 WP_060628228.1 MBL fold metallo-hydrolase Regulator
  RN80_RS06075 (RN80_06090) - 1238868..1239215 (-) 348 WP_060628229.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -
  RN80_RS06080 (RN80_06095) - 1239326..1241044 (-) 1719 WP_060628231.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27109.87 Da        Isoelectric Point: 4.6177

>NTDB_id=156024 RN80_RS06060 WP_049539286.1 1235974..1236681(+) (micA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLTSVDNQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=156024 RN80_RS06060 WP_049539286.1 1235974..1236681(+) (micA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
GGTTGTAACTGCTTTTAATGGCCGTGAAGCGCTAGAACAATTTGAAGCAGAGCAGCCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACTATTCGCAAGACAAGTAGTGTGCCTATTATCATGCTTTCAGCT
AAAGACAGCGAATTTGATAAGGTTATCGGTTTAGAGCTTGGGGCGGATGACTATGTGACCAAACCCTTCTCAAATCGTGA
GTTGCAGGCACGTGTCAAAGCTCTTCTTCGTCGTACAGATTTGACTTCTGTAGATAATCAAGAGTCTGATGAAAAGAAAA
CTCAGCCTTTGCAAATTGGGGACTTGGAGATTGTGCCAGATGCTTATGTGGCTAAAAAATACGGTGAAGAACTAGACTTA
ACTCACCGTGAATTTGAACTCTTGTATCACTTGGCGTCTCATATCGGTCAAGTAATTACGCGTGAACACTTGCTTGAAAC
TGTCTGGGGTTATGATTATTTCGGAGATGTTCGGACTGTCGATGTAACTATCAGACGTTTGCGTGAGAAGATTGAAGATA
CACCAAGTCGTCCTGAGTATATCCTAACACGTCGTGGTGTTGGTTATTATATGAGAAATAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

94.017

99.574

0.936
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

44.589

98.298

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.723

98.298

0.43
  scnR Streptococcus mutans UA159

38.034

99.574

0.379

Multiple sequence alignment