Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   AMM49_RS09475 Genome accession   NZ_CP012480
Coordinates   1894790..1895542 (-) Length   250 a.a.
NCBI ID   WP_001019938.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NGBS128     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1889790..1900542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AMM49_RS09450 (AMM49_09440) - 1890667..1891821 (-) 1155 WP_000623424.1 ABC transporter permease subunit -
  AMM49_RS09455 (AMM49_09445) - 1891827..1892675 (-) 849 WP_000926585.1 ABC transporter ATP-binding protein -
  AMM49_RS09460 (AMM49_09450) - 1892744..1892917 (-) 174 WP_000683602.1 hypothetical protein -
  AMM49_RS09465 (AMM49_09455) - 1893206..1893370 (+) 165 Protein_1779 cysteine peptidase family C39 domain-containing protein -
  AMM49_RS09470 (AMM49_09460) - 1893459..1894793 (-) 1335 WP_001089365.1 sensor histidine kinase -
  AMM49_RS09475 (AMM49_09465) comE/blpR 1894790..1895542 (-) 753 WP_001019938.1 response regulator transcription factor Regulator
  AMM49_RS09480 (AMM49_09470) - 1895758..1896573 (-) 816 WP_001029871.1 endonuclease/exonuclease/phosphatase family protein -
  AMM49_RS09485 (AMM49_09475) - 1896627..1898810 (-) 2184 WP_000795059.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29451.04 Da        Isoelectric Point: 8.4441

>NTDB_id=154616 AMM49_RS09475 WP_001019938.1 1894790..1895542(-) (comE/blpR) [Streptococcus agalactiae strain NGBS128]
MNIFILEDNFIQQARLERIIEEVKIRRSIHSKMVNTFEKPVQLLESICEKGMHNLYFLDIEIKNDEQRGLEVAKQIRQID
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEAFSRRIEDVLLYANNACSKNLLEDSFYFKSRYSQVQVPFNDILY
IETSLRSHRVVLYTAKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRSNKLIYLKNGSNCLISRNKIKDIMVV
IEENQRGRGI

Nucleotide


Download         Length: 753 bp        

>NTDB_id=154616 AMM49_RS09475 WP_001019938.1 1894790..1895542(-) (comE/blpR) [Streptococcus agalactiae strain NGBS128]
GTGAATATTTTTATTTTAGAGGATAATTTTATTCAACAGGCACGTTTAGAGAGAATAATTGAGGAAGTTAAAATTAGGAG
AAGTATACACAGTAAAATGGTAAATACCTTTGAAAAACCAGTTCAATTATTGGAATCAATCTGTGAAAAAGGTATGCATA
ATTTATATTTCTTAGACATTGAAATAAAAAATGATGAGCAGAGGGGCTTAGAGGTCGCAAAACAAATTAGACAAATTGAT
CCTTATGCTCAGATTGTTTTTGTTACAACTCATTCGGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGCATTTAGCAGAAGGATTGAAGACGTTTTACTATATGCTAATAATGCTTGCA
GTAAAAACTTACTAGAAGATTCTTTTTATTTTAAATCACGCTATAGTCAAGTACAAGTACCTTTTAACGATATCCTTTAT
ATAGAAACGTCATTAAGGTCACATAGAGTTGTCCTTTATACTGCAAAAGACAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTGAATATTTTTAAAGTGGATA
GGTCAAATAAACTAATCTATTTAAAAAATGGTTCGAATTGTTTGATTTCTCGTAATAAAATAAAAGATATTATGGTAGTA
ATAGAGGAAAATCAAAGAGGTAGAGGAATATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-238)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

99.6

0.524
  comE/comE1 Streptococcus equinus JB1

42.678

95.6

0.408
  comE Streptococcus pneumoniae D39

38.866

98.8

0.384
  comE Streptococcus pneumoniae R6

38.866

98.8

0.384
  comE Streptococcus pneumoniae TIGR4

38.866

98.8

0.384
  comE Streptococcus mitis SK321

38.866

98.8

0.384
  comE Streptococcus mitis NCTC 12261

38.866

98.8

0.384
  comE Streptococcus pneumoniae Rx1

38.866

98.8

0.384
  comE Streptococcus infantis strain Atu-4

36.8

100

0.368

Multiple sequence alignment