Detailed information NTG0154160

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: A6M16_RS04190
• Genome accession: NZ_CP015557
• Coordinates: 824401..825072 (+)
• Length: 223 a.a.
• NCBI ID: WP_014637852.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DN13
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 819401..830072

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6M16_RS04160 (A6M16_04165)	pstC	819617..820534 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
A6M16_RS04165 (A6M16_04170)	pstA	820524..821411 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
A6M16_RS04170 (A6M16_04175)	pstB	821436..822239 (+)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
A6M16_RS04175 (A6M16_04180)	pstB	822251..823009 (+)	759	WP_024395285.1	phosphate ABC transporter ATP-binding protein PstB	-
A6M16_RS04180 (A6M16_04185)	phoU	823038..823694 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
A6M16_RS04185 (A6M16_04190)	-	823860..824207 (+)	348	WP_014635995.1	hypothetical protein	-
A6M16_RS04190 (A6M16_04195)	ciaR	824401..825072 (+)	672	WP_014637852.1	response regulator transcription factor	Regulator
A6M16_RS04195 (A6M16_04200)	ciaH	825065..826444 (+)	1380	WP_014635993.1	sensor histidine kinase	Regulator
A6M16_RS04200 (A6M16_04205)	-	826544..827773 (+)	1230	WP_024395287.1	transglutaminase domain-containing protein	-
A6M16_RS04205 (A6M16_04210)	tnpA	828150..828614 (+)	465	WP_002939996.1	IS200/IS605-like element ISSsu4 family transposase	-
A6M16_RS04210 (A6M16_04215)	rpsT	828756..829004 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
A6M16_RS04215 (A6M16_04220)	coaA	829063..829983 (-)	921	WP_002940857.1	type I pantothenate kinase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25245.83 Da
• Isoelectric Point: 4.2183

>NTDB_id=154160 A6M16_RS04190 WP_014637852.1 824401..825072(+) (ciaR) [Streptococcus suis strain DN13]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=154160 A6M16_RS04190 WP_014637852.1 824401..825072(+) (ciaR) [Streptococcus suis strain DN13]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTGGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGTATTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACTTATGGGGATGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGCGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTAGTCTAC
TTTTTGCAAAATCAAAATGTTATCTTGCCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.789	100	0.888
ciaR	Streptococcus pneumoniae D39	88.789	100	0.888
ciaR	Streptococcus pneumoniae R6	88.789	100	0.888
ciaR	Streptococcus pneumoniae TIGR4	88.789	100	0.888
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.368