Detailed information NTG0154161

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: A6M16_RS04195
• Genome accession: NZ_CP015557
• Coordinates: 825065..826444 (+)
• Length: 459 a.a.
• NCBI ID: WP_014635993.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DN13
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 820065..831444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6M16_RS04165 (A6M16_04170)	pstA	820524..821411 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
A6M16_RS04170 (A6M16_04175)	pstB	821436..822239 (+)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
A6M16_RS04175 (A6M16_04180)	pstB	822251..823009 (+)	759	WP_024395285.1	phosphate ABC transporter ATP-binding protein PstB	-
A6M16_RS04180 (A6M16_04185)	phoU	823038..823694 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
A6M16_RS04185 (A6M16_04190)	-	823860..824207 (+)	348	WP_014635995.1	hypothetical protein	-
A6M16_RS04190 (A6M16_04195)	ciaR	824401..825072 (+)	672	WP_014637852.1	response regulator transcription factor	Regulator
A6M16_RS04195 (A6M16_04200)	ciaH	825065..826444 (+)	1380	WP_014635993.1	sensor histidine kinase	Regulator
A6M16_RS04200 (A6M16_04205)	-	826544..827773 (+)	1230	WP_024395287.1	transglutaminase domain-containing protein	-
A6M16_RS04205 (A6M16_04210)	tnpA	828150..828614 (+)	465	WP_002939996.1	IS200/IS605-like element ISSsu4 family transposase	-
A6M16_RS04210 (A6M16_04215)	rpsT	828756..829004 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
A6M16_RS04215 (A6M16_04220)	coaA	829063..829983 (-)	921	WP_002940857.1	type I pantothenate kinase	-
A6M16_RS04220 (A6M16_04225)	-	830092..830682 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 459 a.a.
• Molecular weight: 51926.60 Da
• Isoelectric Point: 6.8975

>NTDB_id=154161 A6M16_RS04195 WP_014635993.1 825065..826444(+) (ciaH) [Streptococcus suis strain DN13]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKEAMVESSFGM
SEDYRYVTIELPTDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDT
DRKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide

• Length: 1380 bp

>NTDB_id=154161 A6M16_RS04195 WP_014635993.1 825065..826444(+) (ciaH) [Streptococcus suis strain DN13]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAAAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCAACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAATGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGCCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCTTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCAAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACTGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATACC
GATAGGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterProScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (240-306)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (350-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus pneumoniae Rx1	48.922	100	0.495
ciaH	Streptococcus pneumoniae D39	48.922	100	0.495
ciaH	Streptococcus pneumoniae R6	48.922	100	0.495
ciaH	Streptococcus pneumoniae TIGR4	48.922	100	0.495
ciaH	Streptococcus mutans UA159	49.888	97.386	0.486