Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   MNA02_RS10950 Genome accession   NZ_CP010999
Coordinates   736595..736756 (-) Length   53 a.a.
NCBI ID   WP_014727422.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MN-BM-A02     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 715828..744452 736595..736756 within 0


Gene organization within MGE regions


Location: 715828..744452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MNA02_RS03815 (MNA02_753) - 715828..716424 (+) 597 WP_011225787.1 thymidine kinase -
  MNA02_RS03820 (MNA02_754) prfA 716461..717540 (+) 1080 WP_002948472.1 peptide chain release factor 1 -
  MNA02_RS03825 (MNA02_755) prmC 717537..718370 (+) 834 WP_011681016.1 peptide chain release factor N(5)-glutamine methyltransferase -
  MNA02_RS03830 (MNA02_756) - 718357..718962 (+) 606 WP_002948474.1 L-threonylcarbamoyladenylate synthase -
  MNA02_RS03835 (MNA02_757) glyA 719057..720307 (+) 1251 WP_011227085.1 serine hydroxymethyltransferase -
  MNA02_RS03840 (MNA02_758) - 720314..721291 (+) 978 WP_014608183.1 nucleoid-associated protein -
  MNA02_RS03845 - 721293..721904 (+) 612 WP_014621429.1 lysozyme family protein -
  MNA02_RS03850 (MNA02_760) - 721937..723676 (+) 1740 WP_011681019.1 ABC transporter ATP-binding protein -
  MNA02_RS03855 (MNA02_761) - 723666..725414 (+) 1749 WP_011681020.1 ABC transporter ATP-binding protein -
  MNA02_RS03860 - 725591..725722 (+) 132 WP_002885174.1 teichoic acid D-Ala incorporation-associated protein DltX -
  MNA02_RS03865 (MNA02_763) dltA 725731..727281 (+) 1551 WP_011681022.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  MNA02_RS03870 (MNA02_764) dltB 727278..728525 (+) 1248 WP_014608186.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  MNA02_RS03875 (MNA02_765) dltC 728543..728782 (+) 240 WP_002950439.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  MNA02_RS03880 (MNA02_766) dltD 728775..730043 (+) 1269 WP_011681024.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -
  MNA02_RS10720 - 730096..731445 (-) 1350 Protein_718 IS3 family transposase -
  MNA02_RS03910 (MNA02_772) - 731644..734280 (-) 2637 WP_014621434.1 calcium-translocating P-type ATPase, PMCA-type -
  MNA02_RS03915 (MNA02_773) pabB 734457..736175 (-) 1719 WP_014608193.1 aminodeoxychorismate synthase component I -
  MNA02_RS10950 (MNA02_774) prx 736595..736756 (-) 162 WP_014727422.1 hypothetical protein Regulator
  MNA02_RS03925 (MNA02_775) - 737240..737515 (-) 276 WP_014727423.1 hypothetical protein -
  MNA02_RS03930 (MNA02_776) - 737532..737717 (-) 186 WP_024704073.1 hypothetical protein -
  MNA02_RS03935 (MNA02_777) - 738015..739520 (-) 1506 WP_024704074.1 phage/plasmid primase, P4 family -
  MNA02_RS03940 (MNA02_778) - 739510..740370 (-) 861 WP_024704075.1 primase alpha helix C-terminal domain-containing protein -
  MNA02_RS03945 (MNA02_779) - 740385..740657 (-) 273 WP_011227098.1 MerR family transcriptional regulator -
  MNA02_RS03955 (MNA02_780) - 740900..741136 (-) 237 WP_024704076.1 hypothetical protein -
  MNA02_RS03960 - 741150..741344 (-) 195 WP_024704077.1 hypothetical protein -
  MNA02_RS03965 - 741348..741641 (-) 294 WP_024704078.1 hypothetical protein -
  MNA02_RS03970 (MNA02_782) - 741880..742077 (-) 198 WP_014608200.1 helix-turn-helix domain-containing protein -
  MNA02_RS10095 (MNA02_783) - 742291..742752 (+) 462 WP_405183738.1 helix-turn-helix transcriptional regulator -
  MNA02_RS03980 (MNA02_784) - 742835..744001 (+) 1167 WP_011227104.1 tyrosine-type recombinase/integrase -
  MNA02_RS03985 (MNA02_785) - 744117..744452 (+) 336 WP_002948199.1 hypothetical protein -

Sequence

Protein


Download         Length: 53 a.a.        Molecular weight: 6084.95 Da        Isoelectric Point: 4.2412

>NTDB_id=141253 MNA02_RS10950 WP_014727422.1 736595..736756(-) (prx) [Streptococcus thermophilus strain MN-BM-A02]
MLTYDEFKEAMDKGFIKGDTVQIVRLDGEQVEPREILSLEKVSDIIKELGKDN

Nucleotide


Download         Length: 162 bp        

>NTDB_id=141253 MNA02_RS10950 WP_014727422.1 736595..736756(-) (prx) [Streptococcus thermophilus strain MN-BM-A02]
ATGCTGACTTATGATGAATTTAAAGAGGCAATGGACAAGGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGATTAGA
CGGTGAACAAGTTGAGCCACGCGAAATATTGAGCTTAGAAAAGGTATCGGATATAATAAAGGAACTAGGCAAGGACAACT
AA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

48.333

100

0.547
  prx Streptococcus pyogenes MGAS315

46.667

100

0.528
  prx Streptococcus pyogenes MGAS315

46.667

100

0.528
  prx Streptococcus pyogenes MGAS315

45

100

0.509
  prx Streptococcus pyogenes MGAS315

56.818

83.019

0.472
  prx Streptococcus pyogenes MGAS315

57.143

79.245

0.453
  prx Streptococcus pyogenes MGAS315

60.526

71.698

0.434

Multiple sequence alignment