Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   SD89_RS08460 Genome accession   NZ_CP010449
Coordinates   1684555..1685106 (-) Length   183 a.a.
NCBI ID   WP_080011078.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS322     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1679555..1690106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD89_RS08425 (SD89_08460) - 1679558..1680301 (-) 744 WP_023611041.1 class I SAM-dependent DNA methyltransferase -
  SD89_RS08430 (SD89_08465) rsfS 1680349..1680702 (-) 354 WP_032464231.1 ribosome silencing factor -
  SD89_RS08435 (SD89_08470) yqeK 1680726..1681319 (-) 594 WP_002985989.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  SD89_RS08440 (SD89_08475) - 1681316..1681948 (-) 633 WP_031488555.1 nicotinate-nucleotide adenylyltransferase -
  SD89_RS08445 (SD89_08480) yhbY 1682017..1682325 (-) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  SD89_RS08450 (SD89_08485) yqeH 1682351..1683469 (-) 1119 WP_053308600.1 ribosome biogenesis GTPase YqeH -
  SD89_RS08455 (SD89_08490) - 1683469..1683996 (-) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  SD89_RS08460 (SD89_08495) comX/sigX/comX2/sigX2 1684555..1685106 (-) 552 WP_080011078.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22228.03 Da        Isoelectric Point: 9.8369

>NTDB_id=137352 SD89_RS08460 WP_080011078.1 1684555..1685106(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NGAS322]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
CFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=137352 SD89_RS08460 WP_080011078.1 1684555..1685106(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NGAS322]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
TGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment