Detailed information NTG0133717

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: QI18_RS08165
• Genome accession: NZ_CP010050
• Coordinates: 1651346..1652038 (-)
• Length: 230 a.a.
• NCBI ID: WP_012898209.1
• Uniprot ID: A0AAW7IPJ0
• Organism: Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1646346..1657038

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QI18_RS08150 (QI18_08150)	-	1647965..1648306 (-)	342	WP_010906046.1	P-II family nitrogen regulator	-
QI18_RS08155 (QI18_08155)	-	1648438..1649679 (-)	1242	WP_039115695.1	ammonium transporter	-
QI18_RS08160 (QI18_08160)	covS	1649862..1651337 (-)	1476	WP_010906048.1	HAMP domain-containing histidine kinase	Regulator
QI18_RS08165 (QI18_08165)	covR	1651346..1652038 (-)	693	WP_012898209.1	response regulator transcription factor	Regulator
QI18_RS08170 (QI18_08170)	-	1652194..1652724 (-)	531	WP_012898210.1	YceD family protein	-
QI18_RS08175 (QI18_08175)	-	1652855..1653100 (-)	246	WP_003130760.1	type B 50S ribosomal protein L31	-
QI18_RS08180 (QI18_08180)	-	1653256..1653720 (-)	465	WP_023188701.1	hypothetical protein	-
QI18_RS08185 (QI18_08185)	-	1653802..1654164 (-)	363	WP_023188700.1	TIGR02328 family protein	-
QI18_RS08190 (QI18_08190)	-	1654390..1655301 (-)	912	WP_023188699.1	CHAP domain-containing protein	-
QI18_RS08195 (QI18_08195)	-	1655414..1656250 (-)	837	WP_039115700.1	metallophosphoesterase	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26670.33 Da
• Isoelectric Point: 5.1273

>NTDB_id=133717 QI18_RS08165 WP_012898209.1 1651346..1652038(-) (covR) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEASSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide

• Length: 693 bp

>NTDB_id=133717 QI18_RS08165 WP_012898209.1 1651346..1652038(-) (covR) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTAGAACATGAAGG
CTATGCGACTGAGATTAAAGATAATGGTCGTTCTGGTCTTGAAGAAGCAAGTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (153-226)

• Response regulator receiver domain (Response_reg) (6-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	99.565	100	0.996
covR	Streptococcus salivarius strain HSISS4	68.421	99.13	0.678
vicR	Streptococcus mutans UA159	45.887	100	0.461
micA	Streptococcus pneumoniae Cp1015	43.478	100	0.435
ciaR	Streptococcus mutans UA159	37.611	98.261	0.37
ciaR	Streptococcus pneumoniae Rx1	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae D39	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae R6	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae TIGR4	36.726	98.261	0.361