Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   BG11_RS06675 Genome accession   NZ_CP009596
Coordinates   968341..968922 (+) Length   193 a.a.
NCBI ID   WP_000991625.1    Uniprot ID   A0A2A8KY00
Organism   Bacillus cereus strain 3a     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 955613..971202 968341..968922 within 0


Gene organization within MGE regions


Location: 955613..971202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BG11_RS06590 (BG11_947) - 955613..956419 (+) 807 WP_000540637.1 GH25 family lysozyme -
  BG11_RS06595 (BG11_948) - 956485..956697 (-) 213 WP_000820164.1 DUF3006 domain-containing protein -
  BG11_RS06600 (BG11_949) - 956700..958085 (-) 1386 WP_000714665.1 S-layer homology domain-containing protein -
  BG11_RS06605 (BG11_950) - 958333..958737 (+) 405 WP_000288948.1 GNAT family N-acetyltransferase -
  BG11_RS06610 (BG11_951) - 958750..959085 (+) 336 WP_000994641.1 MmcQ/YjbR family DNA-binding protein -
  BG11_RS06615 (BG11_952) - 959161..959964 (+) 804 WP_000218991.1 DUF1835 domain-containing protein -
  BG11_RS31505 - 960070..960207 (+) 138 Protein_963 MmcQ/YjbR family DNA-binding protein -
  BG11_RS06625 (BG11_953) - 960229..960936 (+) 708 WP_000655495.1 class I SAM-dependent methyltransferase -
  BG11_RS06630 (BG11_954) - 961002..961388 (+) 387 WP_001093446.1 DUF2809 domain-containing protein -
  BG11_RS31830 - 961422..961595 (+) 174 Protein_966 aminoglycoside phosphotransferase -
  BG11_RS06635 (BG11_955) - 961598..962116 (+) 519 WP_001226297.1 DNA topology modulation protein -
  BG11_RS06640 (BG11_956) - 962182..962826 (+) 645 WP_001982255.1 formylglycine-generating enzyme family protein -
  BG11_RS06645 (BG11_957) - 962911..964104 (+) 1194 WP_000124903.1 macrolide family glycosyltransferase -
  BG11_RS06650 (BG11_958) - 964462..965829 (+) 1368 WP_001065248.1 lytic polysaccharide monooxygenase -
  BG11_RS06655 (BG11_959) - 965960..966394 (-) 435 WP_000545576.1 GNAT family N-acetyltransferase -
  BG11_RS06660 (BG11_960) rpiA 966502..967164 (-) 663 WP_000364536.1 ribose 5-phosphate isomerase A -
  BG11_RS06665 (BG11_961) - 967169..967489 (-) 321 WP_001125378.1 2Fe-2S iron-sulfur cluster-binding protein -
  BG11_RS06670 (BG11_962) - 967633..968319 (+) 687 WP_000337490.1 RNA polymerase subunit sigma-70 -
  BG11_RS06675 (BG11_963) clpP 968341..968922 (+) 582 WP_000991625.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  BG11_RS06680 (BG11_964) - 968968..969825 (-) 858 WP_001227634.1 glycine betaine ABC transporter substrate-binding protein -
  BG11_RS06685 (BG11_965) - 969997..971202 (+) 1206 WP_000370609.1 quaternary amine ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21178.42 Da        Isoelectric Point: 5.0776

>NTDB_id=130447 BG11_RS06675 WP_000991625.1 968341..968922(+) (clpP) [Bacillus cereus strain 3a]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=130447 BG11_RS06675 WP_000991625.1 968341..968922(+) (clpP) [Bacillus cereus strain 3a]
ATGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
TCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCTATATTAGATACG
ATGAATTTAATTAAACCAGACGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGCTATTATTATCAGG
TGCAAAAGGAAAACGGTTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCACAAGGGCAAGCGA
CGGAAATTGAAATCACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A8KY00

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

66.667

97.927

0.653
  clpP Streptococcus thermophilus LMD-9

54.688

99.482

0.544
  clpP Streptococcus pneumoniae Rx1

54.688

99.482

0.544
  clpP Streptococcus thermophilus LMG 18311

54.688

99.482

0.544
  clpP Streptococcus pneumoniae D39

54.688

99.482

0.544
  clpP Streptococcus pneumoniae R6

54.688

99.482

0.544
  clpP Streptococcus pneumoniae TIGR4

54.688

99.482

0.544
  clpP Streptococcus pyogenes MGAS315

55.556

97.927

0.544
  clpP Streptococcus pyogenes JRS4

55.556

97.927

0.544
  clpP Streptococcus mutans UA159

53.439

97.927

0.523
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

49.735

97.927

0.487

Multiple sequence alignment