Detailed information NTG0123604

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: FE90_RS07735
• Genome accession: NZ_CP008695
• Coordinates: 1523592..1524182 (-)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain M23ND
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1518592..1529182

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FE90_RS07700 (FE90_1552)	-	1518775..1519167 (-)	393	WP_002985833.1	DUF5684 domain-containing protein	-
FE90_RS07705 (FE90_1553)	rsmI	1519194..1520057 (-)	864	WP_011017425.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
FE90_RS07710 (FE90_1554)	yabA	1520062..1520385 (-)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
FE90_RS09240 (FE90_1556)	-	1520790..1521029 (-)	240	WP_021299187.1	PSP1 C-terminal domain-containing protein	-
FE90_RS07720 (FE90_1557)	-	1521048..1521923 (-)	876	WP_010921931.1	DNA polymerase III subunit delta'	-
FE90_RS07725 (FE90_1558)	tmk	1521941..1522576 (-)	636	WP_038433685.1	dTMP kinase	-
FE90_RS07730 (FE90_1560)	-	1522825..1523100 (-)	276	WP_038433686.1	YlbG family protein	-
FE90_RS07735 (FE90_1561)	clpP	1523592..1524182 (-)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
FE90_RS07740 (FE90_1563)	upp	1524406..1525035 (-)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
FE90_RS07745 (FE90_1564)	-	1525203..1526837 (-)	1635	WP_038433687.1	putative polysaccharide biosynthesis protein	-
FE90_RS07750 (FE90_1565)	-	1526925..1528370 (+)	1446	WP_038433688.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=123604 FE90_RS07735 WP_002985850.1 1523592..1524182(-) (clpP) [Streptococcus pyogenes strain M23ND]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=123604 FE90_RS07735 WP_002985850.1 1523592..1524182(-) (clpP) [Streptococcus pyogenes strain M23ND]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACTAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561