Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DI45_RS08445 Genome accession   NZ_CP007560
Coordinates   1644488..1645051 (-) Length   187 a.a.
NCBI ID   WP_324293904.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS743     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1639488..1650051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DI45_RS08420 (DI45_08725) - 1640867..1641712 (+) 846 WP_002982833.1 mechanosensitive ion channel family protein -
  DI45_RS08425 (DI45_08730) - 1641777..1642337 (-) 561 WP_002982828.1 TIGR01440 family protein -
  DI45_RS08430 (DI45_08735) - 1642351..1642821 (-) 471 WP_002982824.1 ECF transporter S component -
  DI45_RS08435 (DI45_08740) - 1642811..1643575 (-) 765 WP_002988136.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  DI45_RS08440 (DI45_08745) truA 1643565..1644314 (-) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  DI45_RS08445 (DI45_08750) comX/sigX/comX2/sigX2 1644488..1645051 (-) 564 WP_324293904.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 187 a.a.        Molecular weight: 22427.89 Da        Isoelectric Point: 9.5848

>NTDB_id=120858 DI45_RS08445 WP_324293904.1 1644488..1645051(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NGAS743]
MSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQESQ
KRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGERFKGRRALLRKICSFKHLSGAN
VSREDVLYLGRSVPILKNLHSSCKQDL

Nucleotide


Download         Length: 564 bp        

>NTDB_id=120858 DI45_RS08445 WP_324293904.1 1644488..1645051(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NGAS743]
ATGTCGATAGAGACAAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATT
GTGGGATAGAGATGACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGG
AAGAAGAGCGTTTATATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAA
AAGCGTCAGTTCCATAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGTTAGA
CGACTATGTGGCTTATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCAC
TTATCAGGGGCGAACGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATATGCAGTTTCAAGCACTTATCAGGGGCGAAC
GTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAAGAATTTGCACAGCAGTTGTAAGCAAGACCT
ATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

98.039

81.818

0.802
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

98.039

81.818

0.802
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

97.386

81.818

0.797
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

97.386

81.818

0.797
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

97.386

81.818

0.797
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

97.386

81.818

0.797
  comX/sigX Streptococcus mutans UA159

44.937

84.492

0.38
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.65

76.471

0.38
  comX Streptococcus sobrinus strain NIDR 6715-7

47.917

77.005

0.369

Multiple sequence alignment