Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NTHIC486_RS02765 Genome accession   NZ_CP007471
Coordinates   546964..548301 (+) Length   445 a.a.
NCBI ID   WP_005686897.1    Uniprot ID   -
Organism   Haemophilus influenzae strain C486     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 541964..553301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHIC486_RS02740 (NTHIC486_00548) - 542029..544623 (-) 2595 WP_005686901.1 penicillin-binding protein 1A -
  NTHIC486_RS02745 (NTHIC486_00549) comA 544722..545519 (+) 798 WP_005686900.1 pilus assembly protein PilM Machinery gene
  NTHIC486_RS02750 (NTHIC486_00550) comB 545520..546026 (+) 507 WP_005649305.1 competence protein ComB Machinery gene
  NTHIC486_RS02755 (NTHIC486_00551) comC 546023..546544 (+) 522 WP_044345309.1 competence protein ComC Machinery gene
  NTHIC486_RS02760 (NTHIC486_00552) comD 546541..546954 (+) 414 WP_044345311.1 pilus assembly protein PilP Machinery gene
  NTHIC486_RS02765 (NTHIC486_00553) comE 546964..548301 (+) 1338 WP_005686897.1 type IV pilus secretin PilQ family protein Machinery gene
  NTHIC486_RS02770 (NTHIC486_00554) - 548314..549000 (+) 687 WP_005686895.1 ComF family protein -
  NTHIC486_RS02775 (NTHIC486_00555) nfuA 549076..549672 (+) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -
  NTHIC486_RS02780 (NTHIC486_00556) nudC 549739..550533 (+) 795 WP_014550416.1 NAD(+) diphosphatase -
  NTHIC486_RS02785 (NTHIC486_00557) - 550569..551159 (+) 591 WP_005656455.1 YjaG family protein -
  NTHIC486_RS02790 (NTHIC486_00558) - 551299..551571 (+) 273 WP_014550417.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49193.45 Da        Isoelectric Point: 7.8816

>NTDB_id=119739 NTHIC486_RS02765 WP_005686897.1 546964..548301(+) (comE) [Haemophilus influenzae strain C486]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQHDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=119739 NTHIC486_RS02765 WP_005686897.1 546964..548301(+) (comE) [Haemophilus influenzae strain C486]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTAGAGCAATTAGCTTTTCAACATGATG
TCAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGCCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCACACTTAGTGAGTCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.876

100

0.989
  comE Haemophilus influenzae Rd KW20

97.753

100

0.978
  comE Glaesserella parasuis strain SC1401

52.235

95.506

0.499
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.584

0.391
  pilQ Vibrio cholerae strain A1552

42.233

92.584

0.391

Multiple sequence alignment