Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   NTHIC486_RS02745 Genome accession   NZ_CP007471
Coordinates   544722..545519 (+) Length   265 a.a.
NCBI ID   WP_005686900.1    Uniprot ID   -
Organism   Haemophilus influenzae strain C486     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 539722..550519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHIC486_RS02725 (NTHIC486_00545) recR 539891..540493 (-) 603 WP_005626527.1 recombination mediator RecR -
  NTHIC486_RS02730 (NTHIC486_00546) - 540626..540955 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  NTHIC486_RS02735 (NTHIC486_00547) - 541108..541953 (-) 846 WP_005686902.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  NTHIC486_RS02740 (NTHIC486_00548) - 542029..544623 (-) 2595 WP_005686901.1 penicillin-binding protein 1A -
  NTHIC486_RS02745 (NTHIC486_00549) comA 544722..545519 (+) 798 WP_005686900.1 pilus assembly protein PilM Machinery gene
  NTHIC486_RS02750 (NTHIC486_00550) comB 545520..546026 (+) 507 WP_005649305.1 competence protein ComB Machinery gene
  NTHIC486_RS02755 (NTHIC486_00551) comC 546023..546544 (+) 522 WP_044345309.1 competence protein ComC Machinery gene
  NTHIC486_RS02760 (NTHIC486_00552) comD 546541..546954 (+) 414 WP_044345311.1 pilus assembly protein PilP Machinery gene
  NTHIC486_RS02765 (NTHIC486_00553) comE 546964..548301 (+) 1338 WP_005686897.1 type IV pilus secretin PilQ family protein Machinery gene
  NTHIC486_RS02770 (NTHIC486_00554) - 548314..549000 (+) 687 WP_005686895.1 ComF family protein -
  NTHIC486_RS02775 (NTHIC486_00555) nfuA 549076..549672 (+) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 31601.99 Da        Isoelectric Point: 6.2348

>NTDB_id=119735 NTHIC486_RS02745 WP_005686900.1 544722..545519(+) (comA) [Haemophilus influenzae strain C486]
MQFSLKNYRTLQIGIHRKQSYFDFVWFDDLEQPQSYQIFVNDRYFKNRFLQQLKTQYQGKTFPLQFVASIPTHLTWSKVL
MLPQVLNAQECHQQCKFVIEKELPIFLEELWFDYRSTPLKQGFRLEVTAIRKSTAQTYLQDFQPFKINVLDVASNAVLRA
FQYLLNEQVRSENTLFLFQEDDYCLAICERSQQSQILQSHENLTALYEQFTERFEGQLEQVFVYQIPSSHTPLLENWQRV
ETELPFIALGNALWQKDLHQQKVGG

Nucleotide


Download         Length: 798 bp        

>NTDB_id=119735 NTHIC486_RS02745 WP_005686900.1 544722..545519(+) (comA) [Haemophilus influenzae strain C486]
ATGCAATTCTCCCTGAAAAATTACCGCACTTTACAAATCGGCATTCATCGTAAGCAGAGTTATTTTGATTTTGTGTGGTT
TGATGATCTCGAACAGCCACAAAGTTATCAAATCTTTGTTAATGATCGTTATTTTAAAAATCGTTTTTTACAACAGCTAA
AAACACAATATCAAGGGAAAACCTTTCCTTTGCAGTTTGTAGCAAGCATTCCCACTCACTTAACTTGGTCGAAAGTATTA
ATGTTGCCACAAGTGTTAAATGCGCAAGAATGTCATCAACAATGTAAATTTGTGATTGAAAAAGAGCTGCCTATTTTTTT
AGAAGAATTGTGGTTTGATTATCGTTCTACCCCGTTAAAGCAAGGTTTTCGATTAGAGGTTACTGCAATTCGTAAAAGTA
CTGCTCAAACTTATTTGCAAGATTTTCAGCCATTTAAAATTAATGTATTGGATGTTGCGTCAAATGCTGTTTTGCGTGCA
TTTCAATATCTGTTGAATGAACAAGTGCGGTCAGAAAATACCTTATTTTTATTTCAAGAAGATGACTATTGCTTGGCGAT
TTGTGAAAGATCTCAGCAATCACAAATTTTACAATCTCACGAAAATTTGACCGCACTTTATGAACAATTTACCGAACGTT
TTGAAGGACAACTTGAACAAGTTTTTGTTTATCAAATTCCCTCAAGTCATACACCATTACTAGAAAATTGGCAGCGAGTA
GAAACAGAACTCCCTTTTATTGCGCTTGGCAACGCGCTATGGCAAAAAGATTTACATCAACAAAAAGTGGGTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae Rd KW20

98.113

100

0.981
  comA Haemophilus influenzae 86-028NP

96.604

100

0.966

Multiple sequence alignment