Detailed information
Bioinformatically predicted
Overview
| Name | pilA | Type | Machinery gene |
| Locus tag | NTHI477_RS06660 | Genome accession | NZ_CP007470 |
| Coordinates | 1394311..1394760 (-) | Length | 149 a.a. |
| NCBI ID | WP_011271973.1 | Uniprot ID | Q4QNP4 |
| Organism | Haemophilus influenzae strain 477 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 1389311..1399760
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NTHI477_RS06640 (NTHI477_01341) | rho | 1389701..1390963 (+) | 1263 | WP_005648966.1 | transcription termination factor Rho | - |
| NTHI477_RS06645 (NTHI477_01342) | pilD | 1391017..1391709 (-) | 693 | WP_044332408.1 | prepilin peptidase | Machinery gene |
| NTHI477_RS06650 (NTHI477_01343) | pilC | 1391706..1392923 (-) | 1218 | WP_014550481.1 | type II secretion system F family protein | Machinery gene |
| NTHI477_RS06655 (NTHI477_01344) | pilB | 1392920..1394314 (-) | 1395 | WP_011271972.1 | GspE/PulE family protein | Machinery gene |
| NTHI477_RS06660 (NTHI477_01345) | pilA | 1394311..1394760 (-) | 450 | WP_011271973.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | Machinery gene |
| NTHI477_RS06665 (NTHI477_01346) | ampD | 1394875..1395435 (+) | 561 | WP_011271974.1 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | - |
| NTHI477_RS06670 (NTHI477_01347) | corC | 1396057..1396956 (+) | 900 | WP_044332415.1 | CNNM family magnesium/cobalt transport protein CorC | - |
| NTHI477_RS06675 (NTHI477_01348) | lnt | 1396979..1398508 (+) | 1530 | WP_080317215.1 | apolipoprotein N-acyltransferase | - |
| NTHI477_RS06680 (NTHI477_01349) | rsmE | 1398558..1399295 (+) | 738 | WP_044332417.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase | - |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 15572.89 Da Isoelectric Point: 8.0922
>NTDB_id=119702 NTHI477_RS06660 WP_011271973.1 1394311..1394760(-) (pilA) [Haemophilus influenzae strain 477]
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAVSELLQASAPYKADVELCVYSTNETTNCTGGKNGIA
ADITTAKGYVKSVTTSNGAITVKGDGTLANMEYILQATGNAATGVTWTTTCKGTDASLFPANFCGSVTQ
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAVSELLQASAPYKADVELCVYSTNETTNCTGGKNGIA
ADITTAKGYVKSVTTSNGAITVKGDGTLANMEYILQATGNAATGVTWTTTCKGTDASLFPANFCGSVTQ
Nucleotide
Download Length: 450 bp
>NTDB_id=119702 NTHI477_RS06660 WP_011271973.1 1394311..1394760(-) (pilA) [Haemophilus influenzae strain 477]
ATGAAACTAACAACACAGCAAACCTTGAAAAAAGGGTTTACATTAATAGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATTCCCTCTTATCAAAATTATACTAAAAAAGCAGCGGTATCTGAATTACTGCAAGCGTCAGCGC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAACAACAAACTGTACGGGTGGAAAAAATGGTATTGCA
GCAGATATAACCACAGCAAAAGGCTATGTAAAATCAGTGACAACAAGCAACGGTGCAATAACAGTAAAAGGGGATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCTACAGGTAATGCTGCAACAGGTGTAACTTGGACAACAACTTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCGGAAGTGTCACACAATGA
ATGAAACTAACAACACAGCAAACCTTGAAAAAAGGGTTTACATTAATAGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATTCCCTCTTATCAAAATTATACTAAAAAAGCAGCGGTATCTGAATTACTGCAAGCGTCAGCGC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAACAACAAACTGTACGGGTGGAAAAAATGGTATTGCA
GCAGATATAACCACAGCAAAAGGCTATGTAAAATCAGTGACAACAAGCAACGGTGCAATAACAGTAAAAGGGGATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCTACAGGTAATGCTGCAACAGGTGTAACTTGGACAACAACTTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCGGAAGTGTCACACAATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilA | Haemophilus influenzae 86-028NP |
100 |
100 |
1 |
| pilA | Haemophilus influenzae Rd KW20 |
91.946 |
100 |
0.919 |
| pilA | Glaesserella parasuis strain SC1401 |
54.362 |
100 |
0.544 |
| pilA2 | Legionella pneumophila str. Paris |
41.497 |
98.658 |
0.409 |
| pilA2 | Legionella pneumophila strain ERS1305867 |
41.497 |
98.658 |
0.409 |
| pilA | Vibrio campbellii strain DS40M4 |
39.716 |
94.631 |
0.376 |