Detailed information NTG1171307

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DYB47_RS02830
• Genome accession: NZ_UHFV01000002
• Coordinates: 509363..509953 (+)
• Length: 196 a.a.
• NCBI ID: WP_003079031.1
• Uniprot ID: G5JYD0
• Organism: Streptococcus macacae NCTC 11558
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 504363..514953

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS02815 (NCTC11558_00569)	-	506148..507242 (+)	1095	WP_003079223.1	cystathionine gamma-synthase	-
DYB47_RS02820 (NCTC11558_00570)	-	507253..508413 (+)	1161	WP_003081123.1	MalY/PatB family protein	-
DYB47_RS02825 (NCTC11558_00571)	upp	508531..509160 (+)	630	WP_003080738.1	uracil phosphoribosyltransferase	-
DYB47_RS02830 (NCTC11558_00572)	clpP	509363..509953 (+)	591	WP_003079031.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
DYB47_RS02835 (NCTC11558_00573)	-	510141..510581 (+)	441	WP_040841689.1	YlbF family regulator	-
DYB47_RS02840 (NCTC11558_00574)	-	510589..510834 (+)	246	WP_003078477.1	DUF2129 domain-containing protein	-
DYB47_RS02845 (NCTC11558_00575)	-	510936..512105 (+)	1170	WP_003079991.1	ABC transporter substrate-binding protein	-
DYB47_RS02850 (NCTC11558_00576)	-	512736..513605 (+)	870	WP_003081940.1	branched-chain amino acid ABC transporter permease	-
DYB47_RS02855 (NCTC11558_00577)	-	513609..514565 (+)	957	WP_003080474.1	branched-chain amino acid ABC transporter permease	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21671.92 Da
• Isoelectric Point: 5.3292

>NTDB_id=1171307 DYB47_RS02830 WP_003079031.1 509363..509953(+) (clpP) [Streptococcus macacae NCTC 11558]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNSPGGSVSAGLAIVDTMN
FIKSDVQTIVMGVAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGTGGGTQQTDMAIAAEQLLKTRKKLEKILSDNSGK
TVKQIHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=1171307 DYB47_RS02830 WP_003079031.1 509363..509953(+) (clpP) [Streptococcus macacae NCTC 11558]
ATGATTCCTGTAGTTATTGAACAAACGAGCCGCGGAGAACGCTCTTATGATATTTATTCGCGTCTTTTAAAAGATCGCAT
TATTATGCTGACGGGTCCTGTTGAAGATAATATGGCAAATTCTATTATTGCGCAACTTCTTTTCCTTGATGCGCAGGATA
ATACCAAAGATATCTACCTCTATGTTAATTCACCAGGCGGTTCTGTATCTGCTGGATTGGCTATTGTTGATACAATGAAT
TTTATTAAGTCAGATGTGCAGACAATTGTAATGGGAGTTGCAGCTTCAATGGGCACCATTATTGCCTCTAGCGGAACAAA
GGGTAAGCGTTTCATGCTGCCTAATGCTGAATACCTCATTCATCAGCCAATGGGCGGTACAGGCGGCGGTACACAGCAAA
CTGATATGGCTATTGCCGCTGAACAGCTTCTTAAAACCCGTAAGAAATTGGAAAAGATTCTATCAGATAATTCAGGTAAG
ACTGTAAAACAAATTCATAAGGATGCTGAGCGAGATTATTGGATGGATGCCAAAGAAACGCTTAAATATGGCTTTATTGA
TGAAATTATGGAAAATAATGAATTAAAATAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: G5JYD0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	97.449	100	0.974
clpP	Streptococcus pyogenes JRS4	91.837	100	0.918
clpP	Streptococcus pyogenes MGAS315	91.837	100	0.918
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	89.286	100	0.893
clpP	Streptococcus thermophilus LMD-9	88.776	100	0.888
clpP	Lactococcus lactis subsp. cremoris KW2	88.776	100	0.888
clpP	Streptococcus thermophilus LMG 18311	88.776	100	0.888
clpP	Streptococcus pneumoniae Rx1	86.667	99.49	0.862
clpP	Streptococcus pneumoniae D39	86.667	99.49	0.862
clpP	Streptococcus pneumoniae R6	86.667	99.49	0.862
clpP	Streptococcus pneumoniae TIGR4	86.667	99.49	0.862
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561
clpP	Bacillus subtilis subsp. subtilis str. 168	56.122	100	0.561