Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC1   Type   Regulator
Locus tag   ACLV7W_RS10810 Genome accession   NZ_OZ217346
Coordinates   2217167..2217292 (-) Length   41 a.a.
NCBI ID   WP_411865927.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 2212167..2222292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS10785 (SMID22_22160) - 2214294..2214836 (+) 543 WP_001158275.1 TetR/AcrR family transcriptional regulator -
  ACLV7W_RS10800 (SMID22_22190) comE 2215079..2215831 (-) 753 WP_000866073.1 competence system response regulator transcription factor ComE Regulator
  ACLV7W_RS10805 (SMID22_22200) comD 2215828..2217147 (-) 1320 WP_411865926.1 competence system sensor histidine kinase ComD Regulator
  ACLV7W_RS10810 (SMID22_22210) comC/comC1 2217167..2217292 (-) 126 WP_411865927.1 competence-stimulating peptide ComC Regulator
  ACLV7W_RS10820 (SMID22_22230) rlmH 2217575..2218054 (-) 480 WP_000695928.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACLV7W_RS10825 (SMID22_22240) htrA 2218238..2219419 (+) 1182 WP_000681589.1 S1C family serine protease Regulator
  ACLV7W_RS10830 (SMID22_22250) spo0J 2219477..2220235 (+) 759 WP_000410371.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence


Protein


Download         Length: 41 a.a.        Molecular weight: 4882.79 Da        Isoelectric Point: 10.7877

>NTDB_id=1170483 ACLV7W_RS10810 WP_411865927.1 2217167..2217292(-) (comC/comC1) [Streptococcus mitis isolate S. mitis D22]
MKNTVKLEQFVALKEKDLQEIKGGDSRISKFLRDFIFPRKK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=1170483 ACLV7W_RS10810 WP_411865927.1 2217167..2217292(-) (comC/comC1) [Streptococcus mitis isolate S. mitis D22]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCCTTGAAGGAAAAAGACTTGCAGGAGATTAAAGGTGGGGATAGCAG
GATATCAAAATTCCTCCGTGATTTTATTTTCCCAAGAAAAAAGTAA

Domains


Predicted by InterproScan.

(1-31)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC1 Streptococcus pneumoniae R6

82.927

100

0.829

  comC/comC1 Streptococcus pneumoniae G54

82.927

100

0.829

  comC/comC1 Streptococcus pneumoniae D39

82.927

100

0.829

  comC/comC1 Streptococcus pneumoniae Rx1

82.927

100

0.829

  comC Streptococcus mitis SK321

82.927

100

0.829

  comC/comC2 Streptococcus pneumoniae A66

78.049

100

0.78

  comC/comC2 Streptococcus pneumoniae TIGR4

78.049

100

0.78

  comC Streptococcus mitis NCTC 12261

70.37

65.854

0.463


Multiple sequence alignment