Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   ACLV7W_RS06370 Genome accession   NZ_OZ217346
Coordinates   1309784..1310632 (-) Length   282 a.a.
NCBI ID   WP_411865649.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1310814..1312070 1309784..1310632 flank 182


Gene organization within MGE regions


Location: 1309784..1312070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS06370 (SMID22_13090) dprA/cilB/dalA 1309784..1310632 (-) 849 WP_411865649.1 DNA-processing protein DprA Machinery gene
  ACLV7W_RS06375 (SMID22_13100) - 1310814..1312070 (+) 1257 WP_411865650.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31178.84 Da        Isoelectric Point: 5.2151

>NTDB_id=1170448 ACLV7W_RS06370 WP_411865649.1 1309784..1310632(-) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis D22]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIAEISGCRNPAVFMERYFQIDDTHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQSLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=1170448 ACLV7W_RS06370 WP_411865649.1 1309784..1310632(-) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis D22]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAACTGTTGTTGGGTGACATTGCAGAAATTTCAGGTTGCCGAAATCCAGCTGTTTTTATGG
AACGTTATTTTCAGATAGACGATACGCATTTGGAGAAGGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATACGATGCGCCTGTGCTTTTATTTTACAAGGGGAATCTCGACCTCTTGAAATTCCC
GAAGGTAGCAGTCGTAGGAAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAGAGCTTGGAAA
ATGAACTGGTTATCGTCAGTGGATTAGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCTAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTCAGTGAATATGGACCTGGTGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTAATTGTAGCAGAGGCTAAGATGCGCTCAGGTAGTCTCATTACCTGTGAGAGGGCAATGGAAGAA
GGACGCGATGTTTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGTGC
AAAATTGGTCACAAGTGGGCAGGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae D39

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae R6

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

98.582

100

0.986
  dprA/cilB/dalA Streptococcus mitis SK321

97.163

100

0.972
  dprA Streptococcus mutans UA159

63.214

99.291

0.628
  dprA Lactococcus lactis subsp. cremoris KW2

55.714

99.291

0.553
  dprA Acinetobacter baumannii D1279779

35.495

100

0.369
  dprA Haemophilus influenzae Rd KW20

38.202

94.681

0.362

Multiple sequence alignment