Detailed information NTG1170233

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACLV7Z_RS10140
• Genome accession: NZ_OZ217343
• Coordinates: 2031523..2033676 (+)
• Length: 717 a.a.
• NCBI ID: WP_218773990.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis G22
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2026523..2038676

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7Z_RS10110 (SMIG22_20000)	-	2027094..2028080 (-)	987	WP_166730973.1	rhodanese-related sulfurtransferase	-
ACLV7Z_RS10115 (SMIG22_20010)	-	2028276..2029469 (-)	1194	WP_218773991.1	OFA family MFS transporter	-
ACLV7Z_RS10120 (SMIG22_20020)	blpZ	2030008..2030256 (-)	249	WP_112444786.1	immunity protein BlpZ	-
ACLV7Z_RS10125 (SMIG22_20030)	-	2030336..2030554 (-)	219	WP_173213201.1	hypothetical protein	-
ACLV7Z_RS10130 (SMIG22_20040)	-	2030560..2030934 (-)	375	WP_173213199.1	immunity protein	-
ACLV7Z_RS10135 (SMIG22_20050)	-	2030986..2031213 (-)	228	WP_164226314.1	Blp family class II bacteriocin	-
ACLV7Z_RS10140 (SMIG22_20060)	comA/nlmT	2031523..2033676 (+)	2154	WP_218773990.1	peptide cleavage/export ABC transporter BlpA	Regulator
ACLV7Z_RS10145 (SMIG22_20070)	-	2033687..2035048 (+)	1362	WP_218773989.1	bacteriocin secretion accessory protein	-
ACLV7Z_RS10150 (SMIG22_20080)	blpC	2035105..2035245 (+)	141	WP_112444774.1	quorum-sensing system pheromone BlpC	-
ACLV7Z_RS10155 (SMIG22_20090)	-	2035352..2036686 (-)	1335	WP_218757325.1	sensor histidine kinase	-
ACLV7Z_RS10160 (SMIG22_20100)	comE/blpR	2036690..2037439 (-)	750	WP_173253425.1	response regulator transcription factor	Regulator
ACLV7Z_RS10165 (SMIG22_20110)	-	2037436..2037783 (-)	348	WP_218757326.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
ACLV7Z_RS10170 (SMIG22_20120)	-	2037967..2038353 (+)	387	WP_225904702.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80712.78 Da
• Isoelectric Point: 7.6964

>NTDB_id=1170233 ACLV7Z_RS10140 WP_218773990.1 2031523..2033676(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis G22]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNDLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMGFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATHRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPMYMV
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQAPENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQKDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1170233 ACLV7Z_RS10140 WP_218773990.1 2031523..2033676(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis G22]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGATCTACTAAGCTTCCTTCCTCTG
ATTTTCAAGCAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACGATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGGGCTTCTCCAGAGATTATCTCCTAACTGTTCTGAGTCAGAGATTAAGCATTGAT
GTAATTTTGTCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACATCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCCAACTCTATTATAGATGCCTTGGCTTCTACCATTCTCTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGAGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATGTACATGGTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGTTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATCAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTCCAAGCCCCAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTTTTGCGCCGCCATATC
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACCTTGGGTGGTAATCATATGATTAG
CCAAAAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTCGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.608	99.721	0.714
comA	Streptococcus mitis NCTC 12261	66.199	99.442	0.658
comA	Streptococcus pneumoniae Rx1	65.638	99.442	0.653
comA	Streptococcus pneumoniae R6	65.638	99.442	0.653
comA	Streptococcus pneumoniae D39	65.638	99.442	0.653
comA	Streptococcus mitis SK321	65.638	99.442	0.653
comA	Streptococcus gordonii str. Challis substr. CH1	64.903	100	0.65
comA	Streptococcus pneumoniae TIGR4	65.358	99.442	0.65