Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   ACLV7Z_RS07640 Genome accession   NZ_OZ217343
Coordinates   1493990..1494580 (-) Length   196 a.a.
NCBI ID   WP_057487259.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1485893..1499284 1493990..1494580 within 0


Gene organization within MGE regions


Location: 1485893..1499284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS07595 (SMIG22_14900) ftsE 1485893..1486585 (-) 693 WP_000022265.1 cell division ATP-binding protein FtsE -
  ACLV7Z_RS07605 (SMIG22_14920) - 1487805..1488461 (-) 657 WP_218773844.1 CBS domain-containing protein -
  ACLV7Z_RS07610 (SMIG22_14930) - 1488981..1489691 (-) 711 WP_000062200.1 ABC transporter ATP-binding protein -
  ACLV7Z_RS07615 (SMIG22_14940) - 1489691..1490455 (-) 765 WP_001186000.1 ABC transporter ATP-binding protein -
  ACLV7Z_RS07620 (SMIG22_14950) - 1490455..1491411 (-) 957 WP_218773843.1 branched-chain amino acid ABC transporter permease -
  ACLV7Z_RS07625 (SMIG22_14960) - 1491415..1492284 (-) 870 WP_000941427.1 branched-chain amino acid ABC transporter permease -
  ACLV7Z_RS07630 (SMIG22_14970) - 1492400..1493560 (-) 1161 WP_050236908.1 ABC transporter substrate-binding protein -
  ACLV7Z_RS07635 (SMIG22_14980) - 1493645..1493911 (-) 267 WP_218773842.1 YlbG family protein -
  ACLV7Z_RS07640 (SMIG22_14990) clpP 1493990..1494580 (-) 591 WP_057487259.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  ACLV7Z_RS07645 (SMIG22_15000) upp 1494753..1495382 (-) 630 WP_000515975.1 uracil phosphoribosyltransferase -
  ACLV7Z_RS07650 (SMIG22_15010) - 1495471..1495938 (-) 468 WP_000136974.1 deoxycytidylate deaminase -
  ACLV7Z_RS07655 (SMIG22_15020) - 1495957..1496514 (-) 558 WP_218773841.1 TetR/AcrR family transcriptional regulator -
  ACLV7Z_RS07660 (SMIG22_15030) - 1496639..1497484 (+) 846 WP_218773840.1 DegV family protein -
  ACLV7Z_RS07665 (SMIG22_15040) - 1497542..1498714 (+) 1173 WP_218773839.1 NAD(P)/FAD-dependent oxidoreductase -
  ACLV7Z_RS07670 (SMIG22_15050) - 1498763..1499284 (+) 522 WP_175880121.1 DUF1697 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21356.32 Da        Isoelectric Point: 4.4910

>NTDB_id=1170220 ACLV7Z_RS07640 WP_057487259.1 1493990..1494580(-) (clpP) [Streptococcus mitis isolate S. mitis G22]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1170220 ACLV7Z_RS07640 WP_057487259.1 1493990..1494580(-) (clpP) [Streptococcus mitis isolate S. mitis G22]
ATGATTCCTGTCGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTAAAAGACCGCAT
CATTATGCTGACAGGTCCAGTTGAAGACAATATGGCCAACTCTGTTATTGCCCAGTTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCCGTTTCAGCTGGTTTGGCAATTGTTGACACCATGAAC
TTTATCAAGTCAGATGTCCAAACTATCGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTAACACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTTCACGCAGATGCAGAACGCGATAACTGGATGAGTGCTCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

98.98

100

0.99
  clpP Streptococcus pneumoniae D39

98.98

100

0.99
  clpP Streptococcus pneumoniae R6

98.98

100

0.99
  clpP Streptococcus pneumoniae TIGR4

98.98

100

0.99
  clpP Streptococcus thermophilus LMG 18311

93.846

99.49

0.934
  clpP Streptococcus thermophilus LMD-9

93.846

99.49

0.934
  clpP Streptococcus pyogenes JRS4

90.769

99.49

0.903
  clpP Streptococcus pyogenes MGAS315

90.769

99.49

0.903
  clpP Streptococcus mutans UA159

86.735

100

0.867
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

85.641

99.49

0.852
  clpP Lactococcus lactis subsp. cremoris KW2

85.128

99.49

0.847
  clpP Bacillus subtilis subsp. subtilis str. 168

58.854

97.959

0.577
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.031

98.469

0.571

Multiple sequence alignment