Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   ACLV65_RS07190 Genome accession   NZ_OZ217342
Coordinates   1410510..1411100 (-) Length   196 a.a.
NCBI ID   WP_000613475.1    Uniprot ID   F9HD24
Organism   Streptococcus mitis isolate S. mitis B22     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1405510..1416100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS07165 (SMIB22_14050) - 1406212..1406976 (-) 765 WP_001185997.1 ABC transporter ATP-binding protein -
  ACLV65_RS07170 (SMIB22_14060) - 1406976..1407932 (-) 957 WP_411864903.1 branched-chain amino acid ABC transporter permease -
  ACLV65_RS07175 (SMIB22_14070) - 1407936..1408805 (-) 870 WP_000941427.1 branched-chain amino acid ABC transporter permease -
  ACLV65_RS07180 (SMIB22_14080) - 1408921..1410081 (-) 1161 WP_411864904.1 ABC transporter substrate-binding protein -
  ACLV65_RS07185 (SMIB22_14090) - 1410165..1410431 (-) 267 WP_050223575.1 YlbG family protein -
  ACLV65_RS07190 (SMIB22_14100) clpP 1410510..1411100 (-) 591 WP_000613475.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  ACLV65_RS07195 (SMIB22_14110) upp 1411274..1411903 (-) 630 WP_000515974.1 uracil phosphoribosyltransferase -
  ACLV65_RS07200 (SMIB22_14120) - 1411992..1412459 (-) 468 WP_000136973.1 deoxycytidylate deaminase -
  ACLV65_RS07205 (SMIB22_14130) - 1412478..1413035 (-) 558 WP_411864905.1 TetR/AcrR family transcriptional regulator -
  ACLV65_RS07210 (SMIB22_14140) - 1413160..1414005 (+) 846 WP_411864906.1 DegV family protein -
  ACLV65_RS07215 (SMIB22_14150) - 1414064..1415236 (+) 1173 WP_411864907.1 NAD(P)/FAD-dependent oxidoreductase -
  ACLV65_RS07220 (SMIB22_14160) - 1415285..1415806 (+) 522 WP_411864908.1 DUF1697 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21340.32 Da        Isoelectric Point: 4.4910

>NTDB_id=1170136 ACLV65_RS07190 WP_000613475.1 1410510..1411100(-) (clpP) [Streptococcus mitis isolate S. mitis B22]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1170136 ACLV65_RS07190 WP_000613475.1 1410510..1411100(-) (clpP) [Streptococcus mitis isolate S. mitis B22]
ATGATTCCTGTCGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGCCCAGTTGAAGACAATATGGCTAACTCAGTTATTGCCCAGTTGCTTTTCTTAGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCTGTTTCAGCTGGTTTGGCAATTGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACTATCGTGATGGGAATGGCTGCATCTATGGGGACTGTTATTGCATCAAGTGGAGCAAA
AGGCAAGCGTTTCATGCTTCCAAATGCTGAATACATGATCCACCAACCGATGGGTGGTACAGGTGGTGGTACTCAACAAA
CCGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9HD24

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

99.49

100

0.995
  clpP Streptococcus pneumoniae D39

99.49

100

0.995
  clpP Streptococcus pneumoniae R6

99.49

100

0.995
  clpP Streptococcus pneumoniae TIGR4

99.49

100

0.995
  clpP Streptococcus thermophilus LMG 18311

93.333

99.49

0.929
  clpP Streptococcus thermophilus LMD-9

93.333

99.49

0.929
  clpP Streptococcus pyogenes JRS4

91.282

99.49

0.908
  clpP Streptococcus pyogenes MGAS315

91.282

99.49

0.908
  clpP Streptococcus mutans UA159

86.224

100

0.862
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

85.128

99.49

0.847
  clpP Lactococcus lactis subsp. cremoris KW2

84.615

99.49

0.842
  clpP Bacillus subtilis subsp. subtilis str. 168

58.854

97.959

0.577
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.031

98.469

0.571

Multiple sequence alignment