Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   ACLV7Q_RS05620 Genome accession   NZ_OZ217341
Coordinates   1133431..1134279 (-) Length   282 a.a.
NCBI ID   WP_218757321.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Genomic Context

Location: 1128431..1139279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS05595 (SMIC22_10940) - 1128701..1129060 (-) 360 WP_218757320.1 YbaN family protein -
  ACLV7Q_RS05600 - 1129073..1129219 (-) 147 WP_023940225.1 hypothetical protein -
  ACLV7Q_RS05605 (SMIC22_10950) topA 1129317..1131404 (-) 2088 WP_166736708.1 type I DNA topoisomerase -
  ACLV7Q_RS05610 (SMIC22_10960) - 1131570..1132613 (-) 1044 WP_050083959.1 TIGR00341 family protein -
  ACLV7Q_RS05615 (SMIC22_10970) - 1132682..1132834 (-) 153 WP_031222468.1 hypothetical protein -
  ACLV7Q_RS05620 (SMIC22_10980) dprA/cilB/dalA 1133431..1134279 (-) 849 WP_218757321.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31104.81 Da        Isoelectric Point: 5.4157

>NTDB_id=1170043 ACLV7Q_RS05620 WP_218757321.1 1133431..1134279(-) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis C22]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGKDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=1170043 ACLV7Q_RS05620 WP_218757321.1 1133431..1134279(-) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis C22]
ATGAAAATTACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTCCTAGAATA
CGGTGAAAATGTTGATCAAGAATTGTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGGAGAAGGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TACCCTTGGGATTTAAGTGAAATATACGATGCTCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCTTGAAATTTCC
AAAAGTAGCTGTCGTGGGGAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAGGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGATTAGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTAGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTATATTGGCAATGA
CCATCTGGTTCTAAGTGAGTATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAGGAA
GGGCGCGATGTTTTTGCTATACCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGGGC
AAAATTGGTTACAAGTGGGAAGGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae D39

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae R6

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

99.291

100

0.993
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

98.582

100

0.986
  dprA/cilB/dalA Streptococcus mitis SK321

97.872

100

0.979
  dprA Streptococcus mutans UA159

63.214

99.291

0.628
  dprA Lactococcus lactis subsp. cremoris KW2

55.357

99.291

0.55
  dprA Staphylococcus aureus N315

37.809

100

0.379
  dprA Haemophilus influenzae Rd KW20

38.577

94.681

0.365

Multiple sequence alignment