Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   ACKWRP_RS15665 Genome accession   NZ_OZ205032
Coordinates   3014546..3015127 (-) Length   193 a.a.
NCBI ID   WP_000991625.1    Uniprot ID   A0A2A8KY00
Organism   Bacillus cereus biovar anthracis isolate BcbvaCA     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 3012266..3026300 3014546..3015127 within 0


Gene organization within MGE regions


Location: 3012266..3026300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWRP_RS15655 - 3012266..3013471 (-) 1206 WP_000370609.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  ACKWRP_RS15660 - 3013643..3014500 (+) 858 WP_001227635.1 glycine betaine ABC transporter substrate-binding protein -
  ACKWRP_RS15665 clpP 3014546..3015127 (-) 582 WP_000991625.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  ACKWRP_RS15670 - 3015149..3015836 (-) 688 Protein_3026 RNA polymerase subunit sigma-70 -
  ACKWRP_RS15675 - 3015979..3016299 (+) 321 WP_001125380.1 2Fe-2S iron-sulfur cluster-binding protein -
  ACKWRP_RS15680 rpiA 3016304..3016966 (+) 663 WP_410254821.1 ribose 5-phosphate isomerase A -
  ACKWRP_RS15685 - 3017074..3017508 (+) 435 WP_000555719.1 GNAT family N-acetyltransferase -
  ACKWRP_RS15690 - 3017639..3019006 (-) 1368 WP_001065253.1 lytic polysaccharide monooxygenase -
  ACKWRP_RS15695 - 3019443..3019961 (-) 519 WP_000720566.1 DNA topology modulation protein -
  ACKWRP_RS15700 - 3019958..3020137 (-) 180 Protein_3032 aminoglycoside phosphotransferase -
  ACKWRP_RS15705 - 3020189..3020575 (-) 387 WP_001093440.1 DUF2809 domain-containing protein -
  ACKWRP_RS15710 - 3020641..3021348 (-) 708 WP_000655490.1 class I SAM-dependent methyltransferase -
  ACKWRP_RS15715 - 3021370..3021723 (-) 354 WP_000562183.1 MmcQ/YjbR family DNA-binding protein -
  ACKWRP_RS15720 - 3021739..3022143 (-) 405 WP_000288949.1 GNAT family N-acetyltransferase -
  ACKWRP_RS15725 - 3022391..3023776 (+) 1386 WP_000714661.1 S-layer homology domain-containing protein -
  ACKWRP_RS15730 - 3023779..3023991 (+) 213 WP_000820167.1 DUF3006 domain-containing protein -
  ACKWRP_RS15740 - 3025494..3026300 (-) 807 WP_000540635.1 GH25 family lysozyme -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21178.42 Da        Isoelectric Point: 5.0776

>NTDB_id=1169866 ACKWRP_RS15665 WP_000991625.1 3014546..3015127(-) (clpP) [Bacillus cereus biovar anthracis isolate BcbvaCA]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=1169866 ACKWRP_RS15665 WP_000991625.1 3014546..3015127(-) (clpP) [Bacillus cereus biovar anthracis isolate BcbvaCA]
TTGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
CCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCCATATTAGATACG
ATGAATTTAATCAAACCAGACGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGCTATTATTATCAGG
TGCAAAAGGAAAACGGTTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCGCTTGGTGGTGCACAAGGGCAAGCGA
CGGAAATTGAAATCACAGCAAAAAGGATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A8KY00

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

66.667

97.927

0.653
  clpP Streptococcus thermophilus LMD-9

54.688

99.482

0.544
  clpP Streptococcus pneumoniae Rx1

54.688

99.482

0.544
  clpP Streptococcus thermophilus LMG 18311

54.688

99.482

0.544
  clpP Streptococcus pneumoniae D39

54.688

99.482

0.544
  clpP Streptococcus pneumoniae R6

54.688

99.482

0.544
  clpP Streptococcus pneumoniae TIGR4

54.688

99.482

0.544
  clpP Streptococcus pyogenes MGAS315

55.556

97.927

0.544
  clpP Streptococcus pyogenes JRS4

55.556

97.927

0.544
  clpP Streptococcus mutans UA159

53.439

97.927

0.523
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

49.735

97.927

0.487

Multiple sequence alignment