Detailed information NTG1167978

Bioinformatically predicted

Overview

• Name: pilQ
• Type: Machinery gene
• Locus tag: ACFCTL_RS05170
• Genome accession: NZ_OZ182546
• Coordinates: 1110679..1112775 (+)
• Length: 698 a.a.
• NCBI ID: WP_011946023.1
• Uniprot ID: A0A378K6J3
• Organism: Legionella pneumophila isolate ZIB8567
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1105679..1117775

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFCTL_RS05145	-	1106441..1107448 (-)	1008	WP_013101264.1	hypothetical protein	-
ACFCTL_RS05150	pilM	1107865..1108929 (+)	1065	WP_013101265.1	type IV pilus assembly protein PilM	Machinery gene
ACFCTL_RS05155	pilN	1108933..1109481 (+)	549	WP_013101266.1	PilN domain-containing protein	Machinery gene
ACFCTL_RS05160	pilO	1109495..1110094 (+)	600	WP_013101267.1	type 4a pilus biogenesis protein PilO	Machinery gene
ACFCTL_RS05165	pilP	1110091..1110675 (+)	585	WP_013101268.1	pilus assembly protein PilP	Machinery gene
ACFCTL_RS05170	pilQ	1110679..1112775 (+)	2097	WP_011946023.1	type IV pilus secretin PilQ	Machinery gene
ACFCTL_RS05175	aroK	1113222..1113749 (+)	528	WP_010946667.1	shikimate kinase AroK	-
ACFCTL_RS05180	aroB	1113736..1114845 (+)	1110	WP_013101269.1	3-dehydroquinate synthase	-
ACFCTL_RS05185	-	1114842..1116293 (+)	1452	WP_027219627.1	SPOR domain-containing protein	-
ACFCTL_RS05190	-	1116402..1116833 (+)	432	WP_010946670.1	universal stress protein	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 77497.79 Da
• Isoelectric Point: 9.5395

>NTDB_id=1167978 ACFCTL_RS05170 WP_011946023.1 1110679..1112775(+) (pilQ) [Legionella pneumophila isolate ZIB8567]
MRKIIAVLILISASLSMAYPKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTRIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Nucleotide

• Length: 2097 bp

>NTDB_id=1167978 ACFCTL_RS05170 WP_011946023.1 1110679..1112775(+) (pilQ) [Legionella pneumophila isolate ZIB8567]
GTGAGAAAAATTATCGCGGTTTTGATATTAATTAGTGCCAGTTTGAGTATGGCATATCCTAAAGATAATTCACTCATTTC
AGTAAAAGTATTACCATTGCCTGAAAACAGAGTGCGCATTGATTTTCAATTTTCCAAACCCTTAAAGCAGTTGCCCGCAA
GCTTTATTACTCAAAAGCCCCCACGTTTGGTGTTAGATTTTATCAGCACTGATATGCAAATTCCTTCAGATCAGAAAACT
AAAACCATTCAATTAGGCTCATTACATAGCTATAACATTGTTGCTGTTGGGGATAGAGTAAGAGCCATATTGGAGCTGGA
TCGTTCAGTGTCCTATTCTGGCAGTACGGCGGGTTCCGTTTATAGCCTTGTCCTGAATGGTAAAAGCAATGATTTATTTG
AAAATAGCAAGGAAGTATTCATAACGAACCAGGTTGTGAACGCCAAGCATGAAATTAAAAGAATTGATTTTCGTGGTATA
GAAAAGCAGGGCGGTAGAGTTTTAATTGATGTTTCTGATACTGGTATTCCAATTGATGTAACTCAAGTTGGGAAAGAAAT
AGTCGTTAATTTCCTGAATACCAGGATCCCTTTGAATTTAATGAAACGGTATGATGTTTCTGATTTTCACAGCCCTGTGC
AGATTATTACTATGCAACAGGAAGGAAAAAAGGTTCGTATGACCATTCTCAGCAAAGGGGATTATGGGCATTTTGTTTAT
CAGGTCAATAAACAATTTATGGTCGATGTCTTTCCTTTAACTGCGGAAGAAATTCGTCAGGCGAAATTGAAGAAACAGGT
ATTTACCGGTAAACGGATTTCTTTGAATTTCCAGAATATTAGTATTCGAGCTGTGCTTCAACTGCTGGCAGATTTTACCG
GAATCAATATGGTTGTCAGCGACAAAGTGCAAGGAGATATTACGCTAAGATTAAATGATATTCCCTGGGATCAGGCGCTG
GATATCATTTTAACCACACAAGGGTTAGATAAGCGCAGAAAGGGCAACGTCATGTTGATAGATACCAAGGCCTCCATGGA
TAAAATGGAGGAAGAACAACTCAAAAGTCAACAGACAATTGAAAAACTTGAGCCTATTCGTTCTGATTTAATACAGATTA
ATTATGCAAAGGCAGCAGATATTGCTGTTTTGATCAAGGATAAGCAAAATTCCCTATTATCAGACAGAGGAAAAATAAGT
GTTGATGCCAGAACGAATACAATCTGGATTCAGGATACTGGCACCAAAATTGAGGAAGTAAGGGAACTGATAAAGCAATT
GGATATCCCTGTTAAGCAAGTGCTTATTGAGGCAAGAATTGTTGAAGTAACTAAAGATTTTAGTCAAGATATTGGGATAC
GCTGGGGGGTATCAAGACCAACTCACTTAAGTGGTACATTGGAAGGTGCTAACGAGTTAGCGAGAGGAACAGCACCAGCT
AATGTTGTCCCCTTGGAAAGACGATTAAATCTTGATTTGGCAGCTGCTCCTTTAACTGGAGCTACACCGGCCTCGGTAGG
TATTGCTCTAGCCAAGCTTAATGATAACATTCTGCTTGATCTGGAATTGTCTGCTTTGGAAAGTGAAGGGCGTGCTGAAT
TAATATCCAGTCCCCGCCTGATTACTACGAATCAACAGGCAGCAGTCATCGAGTCTGGTGAGGAGATTCCCTATCAGGAG
GCAACATCGAGTGGAGCGACGGCTGTTGCATTTAAAAAAGCAGTGTTGAGTTTGAAAGTTACCCCGCAAATTACGCCTGA
CGGTAAAATTTTGATGGATTTACAGATAAATCAGGATACTCCTTCTCCACAAACATTCCTTGGTGTTCCAGCAATAATAA
CAAAGGAGATTCAGACGAATGTTCTGGTTAATAATGGACAAACCATAGTACTTGGGGGTATTTATAAGCAAGATAAGAAC
AAGGTAATCAATAGAATTCCTTTCTTTGGTGAGTTGCCTGTTGTCGGTATTTTATTTAGTAATAGACAAATCACATTGAA
AAATGAAGAATTACTTATTTTTATTACACCAAGAATAATAACGAATGCCCTATCGATAACAACGATAGAAGGACGTGAAA
AAGATGTTTATAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (525-680)

• AMIN domain (AMIN) (39-113)

• Bacterial type II/III secretion system short domain (Secretin_N) (370-433)

3D structure

• AlphaFold DB: A0A378K6J3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilQ	Legionella pneumophila strain Lp02	99.427	100	0.994
pilQ	Legionella pneumophila strain ERS1305867	99.284	100	0.993
comQ	Acinetobacter baylyi ADP1	38.428	98.424	0.378
pilQ	Pseudomonas aeruginosa PAK	38.102	98.138	0.374