Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   STAB902_RS05815 Genome accession   NZ_CP007041
Coordinates   1107014..1107202 (-) Length   62 a.a.
NCBI ID   WP_011054546.1    Uniprot ID   A0A5S4TJS4
Organism   Streptococcus pyogenes STAB902     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1099426..1146612 1107014..1107202 within 0


Gene organization within MGE regions


Location: 1099426..1146612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAB902_RS05785 (STAB902_06060) pfkA 1099426..1100439 (-) 1014 WP_011054544.1 6-phosphofructokinase -
  STAB902_RS05790 (STAB902_06065) - 1100519..1103629 (-) 3111 WP_011054545.1 DNA polymerase III subunit alpha -
  STAB902_RS05795 (STAB902_06070) - 1103814..1104185 (+) 372 WP_002989617.1 GntR family transcriptional regulator -
  STAB902_RS05800 (STAB902_06075) - 1104185..1104883 (+) 699 WP_032463848.1 ABC transporter ATP-binding protein -
  STAB902_RS05805 (STAB902_06080) - 1104893..1105678 (+) 786 WP_002984433.1 hypothetical protein -
  STAB902_RS05810 (STAB902_06085) - 1105809..1106423 (-) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  STAB902_RS05815 (STAB902_06090) prx 1107014..1107202 (-) 189 WP_011054546.1 hypothetical protein Regulator
  STAB902_RS05820 (STAB902_06095) entC3 1107315..1108097 (-) 783 WP_002988472.1 enterotoxin type C3 EntC3 -
  STAB902_RS05825 (STAB902_06100) - 1108310..1109434 (-) 1125 WP_011054547.1 Fic family protein -
  STAB902_RS05830 (STAB902_06105) - 1109572..1110780 (-) 1209 WP_038432212.1 glucosaminidase domain-containing protein -
  STAB902_RS05840 (STAB902_06115) - 1110896..1111123 (-) 228 WP_003058873.1 phage holin -
  STAB902_RS05845 (STAB902_06120) - 1111120..1111395 (-) 276 WP_002987582.1 hypothetical protein -
  STAB902_RS10110 (STAB902_06125) - 1111405..1112047 (-) 643 Protein_1127 hypothetical protein -
  STAB902_RS05860 (STAB902_06130) - 1112050..1112478 (-) 429 WP_032463849.1 DUF1617 family protein -
  STAB902_RS05865 (STAB902_06135) - 1112490..1114394 (-) 1905 WP_011054442.1 gp58-like family protein -
  STAB902_RS05870 (STAB902_06140) - 1114404..1115411 (-) 1008 WP_011054441.1 hyaluronoglucosaminidase -
  STAB902_RS05875 (STAB902_06145) - 1115408..1117459 (-) 2052 WP_011054440.1 phage tail spike protein -
  STAB902_RS05880 (STAB902_06150) - 1117456..1118226 (-) 771 WP_011017392.1 distal tail protein Dit -
  STAB902_RS05885 (STAB902_06155) - 1118239..1122339 (-) 4101 WP_011054439.1 phage tail tape measure protein -
  STAB902_RS05895 (STAB902_06165) gpG 1122565..1122867 (-) 303 WP_011017390.1 phage tail assembly chaperone G -
  STAB902_RS05900 (STAB902_06170) - 1122960..1123544 (-) 585 WP_011017389.1 major tail protein -
  STAB902_RS05905 (STAB902_06175) - 1123556..1123936 (-) 381 WP_011017388.1 hypothetical protein -
  STAB902_RS05910 (STAB902_06180) - 1123929..1124327 (-) 399 WP_011017387.1 HK97 gp10 family phage protein -
  STAB902_RS05915 (STAB902_06185) - 1124329..1124691 (-) 363 WP_011017386.1 hypothetical protein -
  STAB902_RS05920 (STAB902_06190) - 1124684..1124992 (-) 309 WP_011054437.1 hypothetical protein -
  STAB902_RS10260 - 1124992..1125165 (-) 174 WP_011017384.1 hypothetical protein -
  STAB902_RS05925 (STAB902_06200) - 1125179..1126312 (-) 1134 WP_011017383.1 phage major capsid protein -
  STAB902_RS05930 (STAB902_06205) - 1126329..1127135 (-) 807 WP_011017382.1 head maturation protease, ClpP-related -
  STAB902_RS05935 (STAB902_06210) - 1127116..1128303 (-) 1188 WP_011017381.1 phage portal protein -
  STAB902_RS05940 (STAB902_06215) - 1128456..1128668 (-) 213 WP_136260634.1 hypothetical protein -
  STAB902_RS05945 (STAB902_06220) - 1128671..1130401 (-) 1731 WP_011017380.1 terminase large subunit domain-containing protein -
  STAB902_RS05950 (STAB902_06225) - 1130414..1130731 (-) 318 WP_011017379.1 P27 family phage terminase small subunit -
  STAB902_RS05955 (STAB902_06230) - 1130872..1131177 (-) 306 WP_011017378.1 HNH endonuclease -
  STAB902_RS05960 (STAB902_06235) - 1131170..1131556 (-) 387 WP_011017377.1 hypothetical protein -
  STAB902_RS05965 (STAB902_06240) - 1131582..1131785 (-) 204 WP_011017376.1 hypothetical protein -
  STAB902_RS05970 (STAB902_06245) - 1131843..1132136 (-) 294 WP_011017375.1 hypothetical protein -
  STAB902_RS05975 (STAB902_06250) - 1132290..1132865 (-) 576 WP_011054435.1 site-specific integrase -
  STAB902_RS05980 (STAB902_06255) - 1133025..1133426 (-) 402 WP_011017373.1 hypothetical protein -
  STAB902_RS05985 (STAB902_06260) - 1133441..1134268 (-) 828 WP_011054433.1 prohibitin family protein -
  STAB902_RS05990 (STAB902_06265) - 1134270..1134608 (-) 339 WP_011054432.1 helix-turn-helix domain-containing protein -
  STAB902_RS05995 (STAB902_06270) - 1134605..1134886 (-) 282 WP_011054431.1 hypothetical protein -
  STAB902_RS06000 (STAB902_06275) - 1134901..1135092 (-) 192 Protein_1156 single-stranded DNA-binding protein -
  STAB902_RS06005 - 1135052..1135564 (-) 513 WP_011054429.1 DUF1642 domain-containing protein -
  STAB902_RS06010 (STAB902_06285) - 1135569..1136201 (-) 633 WP_011054428.1 N-6 DNA methylase -
  STAB902_RS06015 (STAB902_06290) - 1136203..1136487 (-) 285 WP_011054427.1 hypothetical protein -
  STAB902_RS06020 (STAB902_06295) - 1136484..1136918 (-) 435 WP_011054426.1 YopX family protein -
  STAB902_RS06025 (STAB902_06300) - 1136935..1137141 (-) 207 WP_011054425.1 hypothetical protein -
  STAB902_RS06030 (STAB902_06305) - 1137155..1137382 (-) 228 WP_011054424.1 hypothetical protein -
  STAB902_RS10375 (STAB902_06310) - 1137382..1138194 (-) 813 Protein_1163 ATP-binding protein -
  STAB902_RS06040 (STAB902_06315) - 1138194..1138955 (-) 762 WP_011054422.1 conserved phage C-terminal domain-containing protein -
  STAB902_RS06045 (STAB902_06320) dnaB 1138948..1140288 (-) 1341 WP_011017360.1 replicative DNA helicase -
  STAB902_RS06050 (STAB902_06325) - 1140275..1140463 (-) 189 WP_032461348.1 hypothetical protein -
  STAB902_RS06055 (STAB902_06330) - 1140584..1140775 (-) 192 WP_011017359.1 hypothetical protein -
  STAB902_RS06060 (STAB902_06340) - 1140868..1141125 (-) 258 WP_011054421.1 hypothetical protein -
  STAB902_RS06065 (STAB902_06345) - 1141199..1141918 (-) 720 WP_011017357.1 ORF6C domain-containing protein -
  STAB902_RS06070 (STAB902_06350) - 1141960..1142469 (+) 510 WP_011106801.1 hypothetical protein -
  STAB902_RS10500 - 1142589..1142723 (-) 135 WP_011017356.1 hypothetical protein -
  STAB902_RS06075 (STAB902_06365) - 1142797..1143009 (-) 213 WP_011054420.1 helix-turn-helix domain-containing protein -
  STAB902_RS06080 (STAB902_06370) - 1143044..1143319 (-) 276 WP_011017354.1 hypothetical protein -
  STAB902_RS06085 (STAB902_06375) - 1143608..1143958 (+) 351 WP_011017353.1 helix-turn-helix domain-containing protein -
  STAB902_RS06090 (STAB902_06380) - 1143962..1144354 (+) 393 WP_011017352.1 ImmA/IrrE family metallo-endopeptidase -
  STAB902_RS06095 (STAB902_06385) - 1144365..1145105 (+) 741 WP_011017351.1 type II toxin-antitoxin system PemK/MazF family toxin -
  STAB902_RS06100 (STAB902_06390) - 1145416..1146612 (+) 1197 WP_011017350.1 tyrosine-type recombinase/integrase -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7226.17 Da        Isoelectric Point: 3.9947

>NTDB_id=116271 STAB902_RS05815 WP_011054546.1 1107014..1107202(-) (prx) [Streptococcus pyogenes STAB902]
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=116271 STAB902_RS05815 WP_011054546.1 1107014..1107202(-) (prx) [Streptococcus pyogenes STAB902]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGATGACGGATATATCGTAGGAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGGAAGCGAGAAATGGAGAAGTTGTGACAGAGGAGAAGGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A5S4TJS4

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS315

84.746

95.161

0.806

  prx Streptococcus pyogenes MGAS8232

84.483

93.548

0.79

  prx Streptococcus pyogenes MGAS315

82.759

93.548

0.774

  prx Streptococcus pyogenes MGAS315

77.966

95.161

0.742

  prx Streptococcus pyogenes MGAS315

87.805

66.129

0.581

  prx Streptococcus pyogenes MGAS315

76.19

67.742

0.516


Multiple sequence alignment