Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG40_RS14195 Genome accession   NZ_CP010150
Coordinates   2748574..2749206 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain D7     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2743574..2754206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG40_RS14170 (RG40_13500) yhfG 2743706..2743873 (+) 168 WP_000736860.1 YhfG family protein -
  RG40_RS14175 (RG40_13505) fic 2743863..2744465 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  RG40_RS14180 (RG40_13510) pabA 2744497..2745060 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  RG40_RS14185 (RG40_13515) argD 2745146..2746366 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG40_RS14190 (RG40_13520) yhfK 2746433..2748523 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  RG40_RS14195 (RG40_13525) crp 2748574..2749206 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG40_RS14205 (RG40_13535) yhfA 2749508..2749912 (+) 405 WP_001148908.1 OsmC family protein -
  RG40_RS14210 (RG40_13540) prkB 2749967..2750836 (-) 870 WP_001274680.1 phosphoribulokinase -
  RG40_RS14215 (RG40_13545) yheU 2750890..2751108 (-) 219 WP_000907085.1 YheU family protein -
  RG40_RS14220 (RG40_13550) yheT 2751102..2752124 (-) 1023 WP_000057405.1 hydrolase -
  RG40_RS14225 (RG40_13555) yheS 2752124..2754037 (-) 1914 WP_073466873.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=116264 RG40_RS14195 WP_000242755.1 2748574..2749206(-) (crp) [Escherichia coli strain D7]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=116264 RG40_RS14195 WP_000242755.1 2748574..2749206(-) (crp) [Escherichia coli strain D7]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment