Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   U8955_RS04865 Genome accession   NZ_OY769914
Coordinates   965996..966703 (+) Length   235 a.a.
NCBI ID   WP_038805201.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 960996..971703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS04840 (SDENT7746_04845) - 961291..961962 (+) 672 WP_038805197.1 GTP pyrophosphokinase -
  U8955_RS04845 (SDENT7746_04850) - 961946..962764 (+) 819 WP_038805198.1 NAD kinase -
  U8955_RS04850 (SDENT7746_04855) - 962761..963657 (+) 897 WP_038805199.1 RluA family pseudouridine synthase -
  U8955_RS04855 (SDENT7746_04860) pta 963700..964674 (+) 975 WP_000451592.1 phosphate acetyltransferase -
  U8955_RS04860 (SDENT7746_04865) mutY 964761..965939 (+) 1179 WP_038805200.1 A/G-specific adenine glycosylase -
  U8955_RS04865 (SDENT7746_04870) micA 965996..966703 (+) 708 WP_038805201.1 response regulator YycF Regulator
  U8955_RS04870 (SDENT7746_04875) micB 966696..968045 (+) 1350 WP_000568724.1 cell wall metabolism sensor histidine kinase VicK Regulator
  U8955_RS04875 (SDENT7746_04880) vicX 968047..968856 (+) 810 WP_038805202.1 MBL fold metallo-hydrolase Regulator
  U8955_RS04880 (SDENT7746_04885) - 968873..969811 (+) 939 WP_125415224.1 hypothetical protein -
  U8955_RS04885 (SDENT7746_04890) - 970235..970582 (-) 348 WP_038805205.1 thiol reductase thioredoxin -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26949.74 Da        Isoelectric Point: 4.6219

>NTDB_id=1161723 U8955_RS04865 WP_038805201.1 965996..966703(+) (micA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MKKILVVDDEKPISDIIKFNMTKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLASADSQESDEKKSQPLQIGDLEILPDAYVAKKYGEELEL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1161723 U8955_RS04865 WP_038805201.1 965996..966703(+) (micA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGACCAAGGAAGGTTATGA
GGTTGTAACGGCCTTTAACGGTAGAGAAGCTATCGAGCTATTTGAGGCAGAGCAACCAGACATTATTATCCTAGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTAGCCAAAGCCATTCGTAAGACGAGTAGTGTGCCTATCATTATGCTCTCAGCC
AAGGATAGTGAGTTTGACAAGGTTATTGGTTTGGAGTTAGGTGCAGATGATTATGTCACAAAGCCTTTCTCAAACCGTGA
ATTGCAGGCGCGTGTCAAGGCATTACTCCGTCGTACAGATCTCGCTTCAGCTGATAGTCAAGAGTCTGATGAAAAGAAAT
CCCAACCCCTACAGATTGGCGATTTGGAAATTCTGCCGGACGCTTACGTAGCCAAAAAATATGGTGAGGAATTAGAGTTG
ACTCATCGTGAGTTTGAGCTCTTGTACCACTTGGCTTCCCATATTGGACAAGTCATTACTCGTGAACACTTACTTGAGAC
TGTTTGGGGCTATGATTATTTTGGTGATGTTCGTACAGTAGACGTGACCATCCGACGTTTGCGTGAAAAGATTGAAGATG
CTCCAAGCCGTCCAGAATACATCCTAACACGTCGTGGTGTGGGGTACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

90.598

99.574

0.902
  vicR Streptococcus mutans UA159

77.021

100

0.77
  covR Streptococcus salivarius strain HSISS4

43.59

99.574

0.434
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.857

98.298

0.421
  scnR Streptococcus mutans UA159

36.481

99.149

0.362

Multiple sequence alignment