Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   U8955_RS04870 Genome accession   NZ_OY769914
Coordinates   966696..968045 (+) Length   449 a.a.
NCBI ID   WP_000568724.1    Uniprot ID   A0A7T3DYU0
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 961696..973045
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS04845 (SDENT7746_04850) - 961946..962764 (+) 819 WP_038805198.1 NAD kinase -
  U8955_RS04850 (SDENT7746_04855) - 962761..963657 (+) 897 WP_038805199.1 RluA family pseudouridine synthase -
  U8955_RS04855 (SDENT7746_04860) pta 963700..964674 (+) 975 WP_000451592.1 phosphate acetyltransferase -
  U8955_RS04860 (SDENT7746_04865) mutY 964761..965939 (+) 1179 WP_038805200.1 A/G-specific adenine glycosylase -
  U8955_RS04865 (SDENT7746_04870) micA 965996..966703 (+) 708 WP_038805201.1 response regulator YycF Regulator
  U8955_RS04870 (SDENT7746_04875) micB 966696..968045 (+) 1350 WP_000568724.1 cell wall metabolism sensor histidine kinase VicK Regulator
  U8955_RS04875 (SDENT7746_04880) vicX 968047..968856 (+) 810 WP_038805202.1 MBL fold metallo-hydrolase Regulator
  U8955_RS04880 (SDENT7746_04885) - 968873..969811 (+) 939 WP_125415224.1 hypothetical protein -
  U8955_RS04885 (SDENT7746_04890) - 970235..970582 (-) 348 WP_038805205.1 thiol reductase thioredoxin -
  U8955_RS04890 (SDENT7746_04895) - 970694..972412 (-) 1719 WP_038805206.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51665.22 Da        Isoelectric Point: 4.6821

>NTDB_id=1161724 U8955_RS04870 WP_000568724.1 966696..968045(+) (micB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKIKDLIAGDYSRVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQETKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGIVKEEALNKSILELLKIEEEYELRDLITQIPE
LMIDSQNANGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTQLDVELINFTAFITFILNRFDKMRSQDEEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1161724 U8955_RS04870 WP_000568724.1 966696..968045(+) (micB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGATTGAAGATATTAGACAAACGATTCTGACCAGTGATTTTATCTTTATTTTGATTTTGCTGGGCTTTATCTTGGTGGT
CACCTTGCTATTGCTAGAAAATCGCCGTGATAATATTCGACTAAAGCAGATTAATCAAAAGATTAAAGATTTAATTGCAG
GAGATTATTCTCGAGTTTTGGATATGCAGGGAAGCTCTGAAATTACCAACATCACCAATAACCTCAATGATTTGTCTGAG
GTCATTCGTTTAACGCAGGAAAATCTGGAGCAAGAAACAAAAAGGCTTAACAGTATTCTTTCTTATATGACAGATGGAGT
TCTTGCAACCAATCGCCGTGGTCAGATTACTATGATTAACGATATGGCTAAGAAACAGCTGGGTATCGTAAAAGAAGAAG
CATTGAACAAAAGCATCCTCGAATTGCTTAAGATAGAGGAAGAGTATGAACTGCGTGACCTCATTACACAGATTCCCGAA
TTGATGATTGATTCCCAAAATGCTAATGGAGAATATCTTAGCCTTCGTGTGCGTTTTGCACTCATTCGTCGTGAGTCTGG
ATTCATCTCTGGTTTGGTTGCCGTTTTGCACGATACGACCGAACAGGAGAAGGAGGAGCGCGAACGGAGACTCTTCGTGT
CCAATGTTAGCCATGAGTTGAGGACTCCTTTGACGAGTGTTAAATCTTATCTTGAAGCCTTAGACGAGGGAGCCTTATAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCGCTTGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATGCGACCACTCAATTGGATGTGGAATTGATTAATTTTACAGCCTTCATCACCTTTATCCTCA
ATCGTTTCGATAAGATGAGGAGCCAGGATGAAGAGAAAAAATATGAGCTGGTTAGAGATTACCCAATCAATTCAGTTTGG
ATCGAAATCGATACTGATAAGATGACCCAGGTGATTGATAATATTCTCAACAATGCCATCAAGTACTCACCAGATGGTGG
AAAAATCACTGTCAGCATGAAAACTACTGATGACCAGATGATTTTATCCATAAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCGAAGATTTTCGACCGTTTTTACCGTGTGGATCGCGCAAGAAGTCGTGCTCAAGGTGGAACTGGTCTAGGT
CTAGCTATCGCCAAGGAAATCATCAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGCTCAACCTT
TACCATAGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DYU0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.522

97.773

0.875
  vicK Streptococcus mutans UA159

70.398

89.532

0.63

Multiple sequence alignment