Detailed information NTG1160545

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ACI6O7_RS09230
• Genome accession: NZ_OY725152
• Coordinates: 1884157..1884804 (-)
• Length: 215 a.a.
• NCBI ID: WP_404378294.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain IMDO WA12L8
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1879157..1889804

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI6O7_RS09205 (LLWA12L8_FAMOGCFE_01850)	atpF	1879227..1879733 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
ACI6O7_RS09210 (LLWA12L8_FAMOGCFE_01851)	atpB	1879748..1880461 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
ACI6O7_RS09215 (LLWA12L8_FAMOGCFE_01852)	-	1880506..1880721 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
ACI6O7_RS09220 (LLWA12L8_FAMOGCFE_01853)	-	1880906..1881682 (-)	777	WP_004255244.1	alpha/beta hydrolase family protein	-
ACI6O7_RS09225 (LLWA12L8_FAMOGCFE_01854)	comEC	1881966..1884176 (-)	2211	WP_404378293.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACI6O7_RS09230 (LLWA12L8_FAMOGCFE_01855)	comEA	1884157..1884804 (-)	648	WP_404378294.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACI6O7_RS09235 (LLWA12L8_FAMOGCFE_01856)	-	1884864..1886225 (-)	1362	WP_029344292.1	ABC transporter permease	-
ACI6O7_RS09240 (LLWA12L8_FAMOGCFE_01857)	-	1886222..1887154 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
ACI6O7_RS09245	-	1887259..1887465 (-)	207	WP_270249665.1	hypothetical protein	-
ACI6O7_RS09250 (LLWA12L8_FAMOGCFE_01858)	-	1887496..1887657 (-)	162	WP_404378295.1	hypothetical protein	-
ACI6O7_RS09255 (LLWA12L8_FAMOGCFE_01859)	-	1887761..1888324 (-)	564	WP_058203965.1	GNAT family N-acetyltransferase	-
ACI6O7_RS09260 (LLWA12L8_FAMOGCFE_01860)	-	1888497..1889675 (-)	1179	WP_404378296.1	SLC13 family permease	-

Sequence

Protein

• Length: 215 a.a.
• Molecular weight: 23654.79 Da
• Isoelectric Point: 4.8659

>NTDB_id=1160545 ACI6O7_RS09230 WP_404378294.1 1884157..1884804(-) (comEA) [Lactococcus lactis strain IMDO WA12L8]
MDKILEKVKEYWKMIVLVVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVSKFSEPNEKSVSKIMVDLKGAVTKP
NVYQISSDERLVDLIKEASGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVTSQVSTTTEKININQAD
LTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

• Length: 648 bp

>NTDB_id=1160545 ACI6O7_RS09230 WP_404378294.1 1884157..1884804(-) (comEA) [Lactococcus lactis strain IMDO WA12L8]
ATGGATAAGATTTTAGAAAAAGTAAAAGAATATTGGAAAATGATTGTTTTAGTTGTTTGTGGGCTCATTGCTGGTGGGAT
TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT
CTGTCAGTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAGCCT
AATGTCTATCAAATTTCGTCAGATGAACGTCTAGTTGATCTAATTAAGGAAGCTAGTGGTTTTACTGACCAAGCTGACCA
GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG
AAAATACTGATAGCTCTGCTAATTCGGTCACTAGTCAAGTCTCAACAACCACTGAAAAAATAAATATCAATCAAGCAGAT
TTGACTGAACTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATCGATTTTCGGACGAAAAATGGTGA
TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAATTGAAAGATGAGTTGTGTT
TTGAATAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (70-125)

• Helix-hairpin-helix motif (HHH_3) (151-212)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	75.688	100	0.767
comEA/celA/cilE	Streptococcus mitis SK321	44.444	100	0.447
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.119	100	0.437
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.096	100	0.419
comEA/celA/cilE	Streptococcus pneumoniae D39	41.096	100	0.419
comEA/celA/cilE	Streptococcus pneumoniae R6	41.096	100	0.419
comEA/celA/cilE	Streptococcus mitis NCTC 12261	41.284	100	0.419
comEA	Latilactobacillus sakei subsp. sakei 23K	36.123	100	0.381