Detailed information NTG1160544

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ACI6O7_RS09225
• Genome accession: NZ_OY725152
• Coordinates: 1881966..1884176 (-)
• Length: 736 a.a.
• NCBI ID: WP_404378293.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain IMDO WA12L8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1876966..1889176

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI6O7_RS09195 (LLWA12L8_FAMOGCFE_01848)	atpA	1877009..1878511 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
ACI6O7_RS09200 (LLWA12L8_FAMOGCFE_01849)	-	1878698..1879225 (-)	528	WP_058213342.1	F0F1 ATP synthase subunit delta	-
ACI6O7_RS09205 (LLWA12L8_FAMOGCFE_01850)	atpF	1879227..1879733 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
ACI6O7_RS09210 (LLWA12L8_FAMOGCFE_01851)	atpB	1879748..1880461 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
ACI6O7_RS09215 (LLWA12L8_FAMOGCFE_01852)	-	1880506..1880721 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
ACI6O7_RS09220 (LLWA12L8_FAMOGCFE_01853)	-	1880906..1881682 (-)	777	WP_004255244.1	alpha/beta hydrolase family protein	-
ACI6O7_RS09225 (LLWA12L8_FAMOGCFE_01854)	comEC	1881966..1884176 (-)	2211	WP_404378293.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACI6O7_RS09230 (LLWA12L8_FAMOGCFE_01855)	comEA	1884157..1884804 (-)	648	WP_404378294.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACI6O7_RS09235 (LLWA12L8_FAMOGCFE_01856)	-	1884864..1886225 (-)	1362	WP_029344292.1	ABC transporter permease	-
ACI6O7_RS09240 (LLWA12L8_FAMOGCFE_01857)	-	1886222..1887154 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
ACI6O7_RS09245	-	1887259..1887465 (-)	207	WP_270249665.1	hypothetical protein	-
ACI6O7_RS09250 (LLWA12L8_FAMOGCFE_01858)	-	1887496..1887657 (-)	162	WP_404378295.1	hypothetical protein	-
ACI6O7_RS09255 (LLWA12L8_FAMOGCFE_01859)	-	1887761..1888324 (-)	564	WP_058203965.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84564.32 Da
• Isoelectric Point: 9.6772

>NTDB_id=1160544 ACI6O7_RS09225 WP_404378293.1 1881966..1884176(-) (comEC) [Lactococcus lactis strain IMDO WA12L8]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDILAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHIGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGKENRYGHPNQETLETLKKYQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=1160544 ACI6O7_RS09225 WP_404378293.1 1881966..1884176(-) (comEC) [Lactococcus lactis strain IMDO WA12L8]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATATCCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTCTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATATTGGAGATTTTTTGAATTTAGCAGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAATTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGAGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAATCCTGACTTTATTAAAGAAATTAACCCCAAACTTGCCCTCATTTCGGTTGGCAAGGAAAATCGAT
ATGGACATCCCAACCAAGAAACTCTAGAAACATTAAAAAAATACCAAATCAGAATACTTAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Competence protein (Competence) (206-446)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	77.174	100	0.772
comEC/celB	Streptococcus mitis SK321	44.34	100	0.447
comEC/celB	Streptococcus mitis NCTC 12261	44.205	100	0.446
comEC/celB	Streptococcus pneumoniae TIGR4	43.472	100	0.439
comEC/celB	Streptococcus pneumoniae Rx1	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae D39	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae R6	43.069	100	0.435