Detailed information
Overview
| Name | prx | Type | Regulator |
| Locus tag | QOR57_RS03185 | Genome accession | NZ_OX461088 |
| Coordinates | 562352..562531 (+) | Length | 59 a.a. |
| NCBI ID | WP_000965651.1 | Uniprot ID | A0AB38VMU0 |
| Organism | Streptococcus agalactiae isolate MRI Z2-338 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 521703..564110 | 562352..562531 | within | 0 |
Gene organization within MGE regions
Location: 521703..564110
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QOR57_RS02910 | - | 521721..522560 (+) | 840 | WP_001035227.1 | SGNH/GDSL hydrolase family protein | - |
| QOR57_RS02915 | - | 522535..523137 (+) | 603 | WP_017647077.1 | YpmS family protein | - |
| QOR57_RS02920 | - | 523240..523515 (+) | 276 | WP_001284634.1 | HU family DNA-binding protein | - |
| QOR57_RS02925 | - | 523603..524745 (-) | 1143 | WP_000269473.1 | site-specific integrase | - |
| QOR57_RS02930 | - | 524860..525411 (-) | 552 | WP_000353930.1 | hypothetical protein | - |
| QOR57_RS02935 | - | 525429..525815 (-) | 387 | WP_000151182.1 | ImmA/IrrE family metallo-endopeptidase | - |
| QOR57_RS02940 | - | 525819..526166 (-) | 348 | WP_000484457.1 | helix-turn-helix transcriptional regulator | - |
| QOR57_RS02945 | - | 526657..527445 (-) | 789 | WP_000092750.1 | hypothetical protein | - |
| QOR57_RS02950 | - | 527496..527687 (+) | 192 | WP_001112862.1 | hypothetical protein | - |
| QOR57_RS02955 | - | 527768..528079 (+) | 312 | WP_001123482.1 | hypothetical protein | - |
| QOR57_RS02960 | - | 528084..528233 (+) | 150 | WP_000732608.1 | hypothetical protein | - |
| QOR57_RS02965 | - | 528227..528454 (+) | 228 | WP_000910901.1 | hypothetical protein | - |
| QOR57_RS02970 | - | 528447..528677 (+) | 231 | WP_225045564.1 | hypothetical protein | - |
| QOR57_RS02975 | - | 528661..529980 (+) | 1320 | WP_000156426.1 | AAA family ATPase | - |
| QOR57_RS02980 | - | 529995..531067 (+) | 1073 | Protein_503 | ATP-binding protein | - |
| QOR57_RS02985 | - | 531163..531786 (+) | 624 | WP_270982287.1 | hypothetical protein | - |
| QOR57_RS02990 | - | 531786..532394 (+) | 609 | WP_001870729.1 | hypothetical protein | - |
| QOR57_RS02995 | - | 532400..533983 (+) | 1584 | WP_032456395.1 | DEAD/DEAH box helicase | - |
| QOR57_RS03000 | - | 533992..534189 (+) | 198 | WP_000427885.1 | hypothetical protein | - |
| QOR57_RS03005 | - | 534182..534433 (-) | 252 | WP_001114109.1 | hypothetical protein | - |
| QOR57_RS03010 | - | 534504..536783 (+) | 2280 | WP_000829573.1 | AAA family ATPase | - |
| QOR57_RS03015 | - | 537153..537386 (+) | 234 | WP_000666343.1 | hypothetical protein | - |
| QOR57_RS03020 | - | 537376..537774 (+) | 399 | WP_000151204.1 | RusA family crossover junction endodeoxyribonuclease | - |
| QOR57_RS03025 | - | 537771..537986 (+) | 216 | WP_000687319.1 | hypothetical protein | - |
| QOR57_RS03030 | - | 537983..538219 (+) | 237 | WP_000145465.1 | DUF3310 domain-containing protein | - |
| QOR57_RS03035 | - | 538216..538446 (+) | 231 | WP_001005355.1 | hypothetical protein | - |
| QOR57_RS03040 | - | 538449..538781 (+) | 333 | WP_000052302.1 | hypothetical protein | - |
| QOR57_RS03045 | - | 538859..539272 (+) | 414 | WP_000041038.1 | transcriptional regulator | - |
| QOR57_RS03050 | - | 539393..539824 (+) | 432 | WP_000041103.1 | terminase small subunit | - |
| QOR57_RS03055 | - | 539814..541094 (+) | 1281 | WP_000208745.1 | PBSX family phage terminase large subunit | - |
| QOR57_RS03060 | - | 541109..542638 (+) | 1530 | WP_000462948.1 | phage portal protein | - |
| QOR57_RS03065 | - | 542598..544046 (+) | 1449 | WP_032457277.1 | phage head morphogenesis protein | - |
| QOR57_RS10300 | - | 544074..544262 (+) | 189 | WP_025194292.1 | hypothetical protein | - |
| QOR57_RS03070 | - | 544267..544470 (+) | 204 | WP_001042286.1 | hypothetical protein | - |
| QOR57_RS03075 | - | 544613..545182 (+) | 570 | WP_000797011.1 | DUF4355 domain-containing protein | - |
| QOR57_RS03080 | - | 545201..546097 (+) | 897 | WP_000818573.1 | hypothetical protein | - |
| QOR57_RS03085 | - | 546103..546459 (+) | 357 | WP_000356705.1 | phage head-tail connector protein | - |
| QOR57_RS03090 | - | 546470..546748 (+) | 279 | WP_000639437.1 | hypothetical protein | - |
| QOR57_RS03095 | - | 546745..547089 (+) | 345 | WP_000060408.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| QOR57_RS03100 | - | 547093..547452 (+) | 360 | WP_000640604.1 | hypothetical protein | - |
| QOR57_RS03105 | - | 547464..548096 (+) | 633 | WP_000450517.1 | phage major tail protein, TP901-1 family | - |
| QOR57_RS03110 | - | 548147..548602 (+) | 456 | WP_000424190.1 | tail assembly chaperone | - |
| QOR57_RS03115 | - | 548677..548907 (+) | 231 | WP_000398752.1 | hypothetical protein | - |
| QOR57_RS03120 | - | 548936..553162 (+) | 4227 | WP_017646851.1 | tape measure protein | - |
| QOR57_RS03125 | - | 553175..554017 (+) | 843 | WP_000365119.1 | phage tail domain-containing protein | - |
| QOR57_RS03130 | - | 554030..557857 (+) | 3828 | WP_283571978.1 | phage tail protein | - |
| QOR57_RS03135 | - | 557866..558018 (+) | 153 | WP_000391486.1 | hypothetical protein | - |
| QOR57_RS03140 | - | 558029..558445 (+) | 417 | WP_001870768.1 | DUF1366 domain-containing protein | - |
| QOR57_RS03145 | - | 558508..558669 (+) | 162 | WP_000222556.1 | hypothetical protein | - |
| QOR57_RS03150 | - | 558679..558975 (+) | 297 | WP_000564987.1 | hypothetical protein | - |
| QOR57_RS03155 | - | 558977..559315 (+) | 339 | WP_001001962.1 | phage holin | - |
| QOR57_RS03160 | - | 559317..560036 (+) | 720 | WP_283571979.1 | peptidoglycan amidohydrolase family protein | - |
| QOR57_RS03165 | - | 560243..561367 (+) | 1125 | WP_001207841.1 | Fic family protein | - |
| QOR57_RS03170 | - | 561521..561721 (+) | 201 | WP_000076696.1 | CsbD family protein | - |
| QOR57_RS03175 | - | 561762..561932 (-) | 171 | WP_000356856.1 | hypothetical protein | - |
| QOR57_RS03180 | - | 562068..562193 (-) | 126 | WP_017646884.1 | hypothetical protein | - |
| QOR57_RS03185 | prx | 562352..562531 (+) | 180 | WP_000965651.1 | hypothetical protein | Regulator |
| QOR57_RS03190 | - | 562937..563134 (+) | 198 | WP_001290370.1 | hypothetical protein | - |
| QOR57_RS03195 | - | 563178..564110 (-) | 933 | WP_000254063.1 | dihydroorotate oxidase | - |
Sequence
Protein
Download Length: 59 a.a. Molecular weight: 7035.07 Da Isoelectric Point: 4.3690
>NTDB_id=1159650 QOR57_RS03185 WP_000965651.1 562352..562531(+) (prx) [Streptococcus agalactiae isolate MRI Z2-338]
MLYIDEFKEAIEKGYISSDTVMVVRKNGKIFDYVLPHEKVREEEVVTVERVEDVMRELE
MLYIDEFKEAIEKGYISSDTVMVVRKNGKIFDYVLPHEKVREEEVVTVERVEDVMRELE
Nucleotide
Download Length: 180 bp
>NTDB_id=1159650 QOR57_RS03185 WP_000965651.1 562352..562531(+) (prx) [Streptococcus agalactiae isolate MRI Z2-338]
ATGTTATACATAGATGAGTTTAAAGAAGCGATTGAAAAAGGATATATCAGCAGTGATACAGTGATGGTTGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGAAGAAGAGGTTGTGACAGTTGAGAGAGTGGAAGATG
TTATGAGAGAATTGGAGTAA
ATGTTATACATAGATGAGTTTAAAGAAGCGATTGAAAAAGGATATATCAGCAGTGATACAGTGATGGTTGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGAAGAAGAGGTTGTGACAGTTGAGAGAGTGGAAGATG
TTATGAGAGAATTGGAGTAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
66.102 |
100 |
0.661 |
| prx | Streptococcus pyogenes MGAS315 |
66.102 |
100 |
0.661 |
| prx | Streptococcus pyogenes MGAS8232 |
67.241 |
98.305 |
0.661 |
| prx | Streptococcus pyogenes MGAS315 |
65.517 |
98.305 |
0.644 |
| prx | Streptococcus pyogenes MGAS315 |
83.721 |
72.881 |
0.61 |
| prx | Streptococcus pyogenes MGAS315 |
71.429 |
71.186 |
0.508 |
| prx | Streptococcus pyogenes MGAS315 |
69.767 |
72.881 |
0.508 |