Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   QOR48_RS09535 Genome accession   NZ_OX460942
Coordinates   1871775..1872527 (-) Length   250 a.a.
NCBI ID   WP_283573058.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate MRI Z2-158     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1866775..1877527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR48_RS09505 - 1866832..1867323 (-) 492 WP_000632643.1 PTS sugar transporter subunit IIB -
  QOR48_RS09510 - 1867341..1867766 (-) 426 WP_000823120.1 PTS mannose transporter subunit IIA -
  QOR48_RS09515 - 1868013..1869047 (-) 1035 WP_000369172.1 hypothetical protein -
  QOR48_RS09520 - 1869276..1870430 (-) 1155 WP_283573057.1 ABC transporter permease subunit -
  QOR48_RS09525 - 1870436..1871284 (-) 849 WP_000926588.1 ABC transporter ATP-binding protein -
  QOR48_RS09530 - 1871407..1871706 (-) 300 WP_000002567.1 GHKL domain-containing protein -
  QOR48_RS09535 comE/blpR 1871775..1872527 (-) 753 WP_283573058.1 response regulator transcription factor Regulator
  QOR48_RS09540 - 1872804..1873619 (-) 816 WP_001029868.1 endonuclease/exonuclease/phosphatase family protein -
  QOR48_RS09545 - 1873673..1875856 (-) 2184 WP_000795063.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29745.25 Da        Isoelectric Point: 6.6452

>NTDB_id=1159211 QOR48_RS09535 WP_283573058.1 1871775..1872527(-) (comE/blpR) [Streptococcus agalactiae isolate MRI Z2-158]
MNIFILEDDFVQQAHFEKIIKEIRVQYNLRFKTVETFAKPVQLLESIYEIGLHNLFFLDIEIKNDEQMGLEVAKQIRQVD
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEEFSQRIEEVLLYVDGICNKPLVENSFYFKSRYSQVQLPFNDLLY
IETSSRSHRVVLYTEKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRIDRLVYFQNGTTCLVSRNKVRDIVSI
VDKYQKDRKR

Nucleotide


Download         Length: 753 bp        

>NTDB_id=1159211 QOR48_RS09535 WP_283573058.1 1871775..1872527(-) (comE/blpR) [Streptococcus agalactiae isolate MRI Z2-158]
GTGAATATTTTTATACTTGAGGATGATTTTGTTCAACAAGCCCATTTTGAAAAAATCATTAAAGAGATTAGAGTACAGTA
CAATCTGCGTTTCAAAACAGTAGAAACGTTTGCTAAACCAGTTCAATTATTGGAATCAATTTATGAAATAGGTTTACATA
ATTTATTTTTCTTAGATATTGAAATAAAAAATGATGAGCAGATGGGCTTAGAGGTAGCAAAACAAATTAGACAAGTTGAT
CCATATGCTCAGATTGTTTTTGTTACAACTCATTCAGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGAGTTTAGCCAAAGGATTGAGGAAGTATTGTTGTACGTAGATGGCATTTGCA
ATAAGCCCTTAGTGGAAAATTCATTCTACTTTAAGTCGCGTTACAGCCAGGTACAATTACCTTTTAACGATCTTCTTTAT
ATAGAAACATCCTCAAGATCACATAGAGTTGTCCTTTATACTGAAAAAGATAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTAAATATTTTTAAAGTGGATA
GGATAGATAGATTAGTTTACTTCCAAAATGGAACGACTTGTCTGGTTTCACGCAATAAAGTGAGAGATATAGTATCTATA
GTGGATAAATATCAAAAGGATAGAAAAAGATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-238)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.479

96.8

0.508
  comE/comE1 Streptococcus equinus JB1

41.564

97.2

0.404
  comE Streptococcus infantis strain Atu-4

37.052

100

0.372
  comE Streptococcus mitis NCTC 12261

37.2

100

0.372
  comE Streptococcus mitis SK321

36.653

100

0.368
  comE Streptococcus pneumoniae D39

36.694

99.2

0.364
  comE Streptococcus pneumoniae R6

36.694

99.2

0.364
  comE Streptococcus pneumoniae TIGR4

36.694

99.2

0.364
  comE Streptococcus pneumoniae Rx1

36.694

99.2

0.364

Multiple sequence alignment