Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   QOR46_RS10110 Genome accession   NZ_OX460934
Coordinates   2000202..2000954 (-) Length   250 a.a.
NCBI ID   WP_001019933.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate MRI Z2-335     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1995202..2005954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR46_RS10075 - 1995259..1995750 (-) 492 WP_000632641.1 PTS sugar transporter subunit IIB -
  QOR46_RS10080 - 1995768..1996193 (-) 426 WP_000823122.1 PTS mannose transporter subunit IIA -
  QOR46_RS10085 - 1996441..1997475 (-) 1035 WP_000369169.1 acyltransferase family protein -
  QOR46_RS10090 - 1997704..1998858 (-) 1155 WP_000623426.1 ABC transporter permease subunit -
  QOR46_RS10095 - 1998864..1999712 (-) 849 WP_000926589.1 ABC transporter ATP-binding protein -
  QOR46_RS11070 - 1999835..2000133 (-) 299 Protein_1915 GHKL domain-containing protein -
  QOR46_RS10110 comE/blpR 2000202..2000954 (-) 753 WP_001019933.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  QOR46_RS10115 - 2001231..2002046 (-) 816 WP_001029869.1 endonuclease/exonuclease/phosphatase family protein -
  QOR46_RS10120 - 2002100..2004283 (-) 2184 WP_000795065.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29688.18 Da        Isoelectric Point: 6.4980

>NTDB_id=1158952 QOR46_RS10110 WP_001019933.1 2000202..2000954(-) (comE/blpR) [Streptococcus agalactiae isolate MRI Z2-335]
MNIFILEDDFVQQAHLEKIIKEIRVQYNLHFKTVETFAKPVQLLESIYEIGLHNLFFLDIEIKNDEQIGLEVAKQIRQVD
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEEFSQRIEEVLLYVDGICNKPLVENSFYFKSRYSQVQLPFNDLLY
IETSSRSHRVVLYTEKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRIDRLVYFQNGTTCLISRNKVRDIVSI
VDKYQKDRKR

Nucleotide


Download         Length: 753 bp        

>NTDB_id=1158952 QOR46_RS10110 WP_001019933.1 2000202..2000954(-) (comE/blpR) [Streptococcus agalactiae isolate MRI Z2-335]
GTGAATATTTTTATACTTGAGGATGATTTTGTTCAACAAGCCCATTTGGAAAAAATCATTAAAGAGATTAGAGTACAGTA
CAATCTGCATTTCAAAACAGTAGAAACGTTTGCTAAACCAGTTCAATTATTGGAGTCAATTTATGAAATAGGTTTGCATA
ATTTATTTTTCTTAGATATTGAAATAAAAAACGATGAGCAGATAGGCTTAGAGGTCGCAAAACAAATTAGACAAGTTGAT
CCTTATGCTCAGATTGTTTTTGTTACAACTCATTCAGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGAGTTTAGCCAAAGGATTGAGGAAGTATTGTTGTACGTAGATGGCATTTGCA
ATAAGCCCTTAGTGGAAAATTCATTCTACTTTAAGTCGCGTTACAGCCAGGTACAATTACCTTTTAACGATCTTCTTTAT
ATAGAAACATCCTCAAGATCACATAGAGTTGTCCTTTATACTGAAAAAGATAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTAAATATTTTTAAAGTGGATA
GGATAGATAGATTAGTTTACTTCCAAAATGGAACGACTTGTCTGATTTCACGCAATAAAGTGAGAGATATAGTATCTATA
GTGGATAAATATCAAAAGGATAGAAAAAGATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-238)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.306

96.8

0.516
  comE/comE1 Streptococcus equinus JB1

41.152

97.2

0.4
  comE Streptococcus infantis strain Atu-4

37.849

100

0.38
  comE Streptococcus mitis NCTC 12261

38

100

0.38
  comE Streptococcus mitis SK321

38

100

0.38
  comE Streptococcus pneumoniae R6

37.5

99.2

0.372
  comE Streptococcus pneumoniae TIGR4

37.5

99.2

0.372
  comE Streptococcus pneumoniae Rx1

37.5

99.2

0.372
  comE Streptococcus pneumoniae D39

37.5

99.2

0.372

Multiple sequence alignment