Detailed information NTG1158941

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: QOR46_RS05455
• Genome accession: NZ_OX460934
• Coordinates: 1035757..1036599 (-)
• Length: 280 a.a.
• NCBI ID: WP_001015250.1
• Uniprot ID: X5JZS7
• Organism: Streptococcus agalactiae isolate MRI Z2-335
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1030757..1041599

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR46_RS05445	-	1032704..1033405 (-)	702	WP_000120354.1	ABC transporter ATP-binding protein	-
QOR46_RS05450	topA	1033542..1035662 (-)	2121	WP_000246609.1	type I DNA topoisomerase	-
QOR46_RS05455	dprA	1035757..1036599 (-)	843	WP_001015250.1	DNA-processing protein DprA	Machinery gene
QOR46_RS05460	-	1036737..1037765 (-)	1029	WP_000162771.1	siderophore ABC transporter substrate-binding protein	-
QOR46_RS05465	-	1037827..1038588 (-)	762	WP_000614757.1	ATP-binding cassette domain-containing protein	-
QOR46_RS05470	-	1038585..1039559 (-)	975	WP_000588582.1	iron chelate uptake ABC transporter family permease subunit	-
QOR46_RS05475	-	1039556..1040518 (-)	963	WP_000735584.1	iron chelate uptake ABC transporter family permease subunit	-
QOR46_RS05480	-	1040757..1041305 (-)	549	WP_000136503.1	sugar O-acetyltransferase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31271.32 Da
• Isoelectric Point: 9.3800

>NTDB_id=1158941 QOR46_RS05455 WP_001015250.1 1035757..1036599(-) (dprA) [Streptococcus agalactiae isolate MRI Z2-335]
MNHFELFKLKKAGLTNLNINNIINYLKKNSLTSLSVRNMAVVSKCKNPTFFIENYKQLDLKKLRQEFKKFPVLSILDSNY
PLELKEIYNPPVLLFYQGNIELLSKPKLAVVGARQASQIGCQSVKKIIKETNNQFVIVSGLARGIDTAAHVSALKNGGSS
IAVIGSGLDVYYPTENKKLQEYMSYNHLVLSEYFTGEQPLKFHFPERNRIIAGLCQGIVVAEAKMRSGSLITCERALEEG
REVFAIPGNIIDGKSDGCHHLIQEGAKCIISGKDILSEYQ

Nucleotide

• Length: 843 bp

>NTDB_id=1158941 QOR46_RS05455 WP_001015250.1 1035757..1036599(-) (dprA) [Streptococcus agalactiae isolate MRI Z2-335]
ATGAATCATTTTGAACTATTTAAGCTTAAAAAAGCTGGACTAACAAATCTTAATATCAACAATATTATCAACTACCTTAA
AAAGAATAGTTTAACTTCTCTATCTGTTCGCAATATGGCCGTAGTGTCAAAATGTAAAAACCCTACTTTCTTTATAGAAA
ATTATAAACAGCTAGACCTTAAAAAACTTCGACAAGAATTCAAAAAATTTCCAGTTCTATCGATTTTGGATTCTAACTAT
CCTTTAGAGTTAAAAGAAATATATAATCCACCAGTTCTACTTTTTTATCAGGGTAATATTGAACTTCTATCTAAACCTAA
ATTAGCTGTAGTGGGAGCAAGACAGGCATCTCAGATAGGTTGTCAGTCTGTTAAAAAGATTATCAAGGAGACTAACAATC
AATTTGTTATCGTAAGTGGTTTAGCGCGTGGCATTGATACAGCAGCACATGTTAGTGCTTTAAAAAATGGAGGCAGTAGT
ATAGCTGTTATCGGGAGTGGTTTAGATGTTTATTATCCAACGGAGAATAAGAAACTTCAAGAATATATGTCATATAATCA
TCTCGTATTATCAGAATATTTTACCGGAGAACAACCCTTGAAATTTCATTTCCCCGAACGTAACCGTATTATTGCAGGGC
TATGTCAAGGTATTGTGGTTGCCGAAGCTAAGATGAGATCTGGAAGTTTAATTACCTGTGAAAGAGCATTAGAAGAGGGA
CGAGAAGTTTTTGCCATTCCCGGAAATATTATCGATGGCAAATCAGATGGATGCCATCATCTTATCCAAGAAGGAGCTAA
ATGCATTATTTCAGGAAAAGATATCCTTTCTGAATATCAGTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-63)

3D structure

• AlphaFold DB: X5JZS7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70.251	99.643	0.7
dprA/cilB/dalA	Streptococcus mitis SK321	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.786	100	0.618
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	61.429	100	0.614
dprA	Lactococcus lactis subsp. cremoris KW2	61.29	99.643	0.611
dprA	Latilactobacillus sakei subsp. sakei 23K	42.231	89.643	0.379
dprA	Haemophilus influenzae Rd KW20	37.132	97.143	0.361