Detailed information NTG1157774

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: KJP47_RS18615
• Genome accession: NZ_OX419577
• Coordinates: 3473380..3473973 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis isolate NRS6120
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3468380..3478973

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP47_RS18585 (NRS6120_19140)	aspP	3469355..3470917 (+)	1563	WP_213381999.1	APC family permease	-
KJP47_RS18590 (NRS6120_19145)	-	3471012..3471596 (+)	585	WP_003228226.1	TetR family transcriptional regulator	-
KJP47_RS18595 (NRS6120_19150)	psmA	3471678..3472013 (+)	336	WP_014480966.1	SMR family transporter	-
KJP47_RS18600 (NRS6120_19155)	psmB	3472013..3472333 (+)	321	WP_208555996.1	multidrug efflux SMR transporter	-
KJP47_RS18605 (NRS6120_19160)	yvdQ	3472369..3472877 (-)	509	Protein_3604	DUF3231 family protein	-
KJP47_RS18615 (NRS6120_19170)	clpP	3473380..3473973 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
KJP47_RS18620 (NRS6120_19175)	pgmB	3474035..3474709 (-)	675	WP_017695258.1	beta-phosphoglucomutase	-
KJP47_RS18625 (NRS6120_19180)	malL	3474706..3476391 (-)	1686	WP_041333260.1	oligo-1,6-glucosidase	-
KJP47_RS18630 (NRS6120_19185)	mdxK	3476384..3478657 (-)	2274	WP_213382063.1	glycoside hydrolase family 65 protein	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=1157774 KJP47_RS18615 WP_003228214.1 3473380..3473973(+) (clpP) [Bacillus subtilis isolate NRS6120]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=1157774 KJP47_RS18615 WP_003228214.1 3473380..3473973(+) (clpP) [Bacillus subtilis isolate NRS6120]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGCATGGCTGCGTCAATGGGCGCGTTCCTACTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538