Detailed information NTG1157529

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: KJP57_RS19375
• Genome accession: NZ_OX419573
• Coordinates: 3657846..3658439 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis isolate NRS6085
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3652846..3663439

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP57_RS19340 (NRS6085_19285)	-	3653832..3654416 (+)	585	WP_175405003.1	TetR family transcriptional regulator	-
KJP57_RS19345 (NRS6085_19290)	psmA	3654498..3654833 (+)	336	WP_014480966.1	SMR family transporter	-
KJP57_RS19350 (NRS6085_19295)	psmB	3654833..3655153 (+)	321	WP_021480661.1	QacE family quaternary ammonium compound efflux SMR transporter	-
KJP57_RS19355 (NRS6085_19300)	yvdQ	3655189..3655701 (-)	513	WP_014478056.1	DUF3231 family protein	-
KJP57_RS19360	-	3655767..3655931 (+)	165	WP_250629532.1	hypothetical protein	-
KJP57_RS19365 (NRS6085_19305)	cotR	3656180..3657142 (+)	963	WP_024573362.1	sporulation hydrolase CotR	-
KJP57_RS19375 (NRS6085_19315)	clpP	3657846..3658439 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
KJP57_RS19380 (NRS6085_19320)	pgmB	3658483..3659157 (-)	675	WP_213407961.1	beta-phosphoglucomutase	-
KJP57_RS19385 (NRS6085_19325)	malL	3659154..3660839 (-)	1686	WP_163131468.1	oligo-1,6-glucosidase	-
KJP57_RS19390 (NRS6085_19330)	mdxK	3660832..3663105 (-)	2274	WP_163131585.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=1157529 KJP57_RS19375 WP_003228214.1 3657846..3658439(+) (clpP) [Bacillus subtilis isolate NRS6085]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=1157529 KJP57_RS19375 WP_003228214.1 3657846..3658439(+) (clpP) [Bacillus subtilis isolate NRS6085]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAAGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGTGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538