Detailed information NTG1157106

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: KJP48_RS18720
• Genome accession: NZ_OX419564
• Coordinates: 3552579..3553172 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis isolate NRS6127
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3547579..3558172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP48_RS18690 (NRS6127_18545)	psmA	3547834..3548169 (+)	336	WP_014480966.1	SMR family transporter	-
KJP48_RS18695 (NRS6127_18550)	psmB	3548169..3548489 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
KJP48_RS18700 (NRS6127_18555)	yvdQ	3548525..3549037 (-)	513	WP_003243249.1	DUF3231 family protein	-
KJP48_RS18705 (NRS6127_18560)	cotNP	3549289..3550632 (-)	1344	WP_029725961.1	FAD-binding oxidoreductase	-
KJP48_RS18710 (NRS6127_18565)	cotR	3550988..3551950 (+)	963	WP_029725962.1	sporulation hydrolase CotR	-
KJP48_RS18720 (NRS6127_18575)	clpP	3552579..3553172 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
KJP48_RS18725 (NRS6127_18580)	pgmB	3553244..3553909 (-)	666	WP_029725963.1	beta-phosphoglucomutase	-
KJP48_RS18730 (NRS6127_18585)	malL	3553906..3555591 (-)	1686	WP_029725964.1	oligo-1,6-glucosidase	-
KJP48_RS18735 (NRS6127_18590)	mdxK	3555584..3557857 (-)	2274	WP_029725965.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=1157106 KJP48_RS18720 WP_003228214.1 3552579..3553172(+) (clpP) [Bacillus subtilis isolate NRS6127]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=1157106 KJP48_RS18720 WP_003228214.1 3552579..3553172(+) (clpP) [Bacillus subtilis isolate NRS6127]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
GGAAAAAGGCAAACGCTATGCACTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGTGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538