Detailed information NTG1156546

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: KJP78_RS18950
• Genome accession: NZ_OX419553
• Coordinates: 3586336..3586929 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis isolate NRS6183
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3581336..3591929

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP78_RS18920 (NRS6183_18760)	psmA	3581591..3581926 (+)	336	WP_014480966.1	SMR family transporter	-
KJP78_RS18925 (NRS6183_18765)	psmB	3581926..3582246 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
KJP78_RS18930 (NRS6183_18770)	yvdQ	3582282..3582794 (-)	513	WP_003243249.1	DUF3231 family protein	-
KJP78_RS18935 (NRS6183_18775)	cotNP	3583046..3584389 (-)	1344	WP_213416689.1	FAD-binding oxidoreductase	-
KJP78_RS18940 (NRS6183_18780)	cotR	3584745..3585707 (+)	963	WP_029725962.1	sporulation hydrolase CotR	-
KJP78_RS18950 (NRS6183_18790)	clpP	3586336..3586929 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
KJP78_RS18955 (NRS6183_18795)	pgmB	3587001..3587666 (-)	666	WP_029725963.1	beta-phosphoglucomutase	-
KJP78_RS18960 (NRS6183_18800)	malL	3587663..3589348 (-)	1686	WP_029725964.1	oligo-1,6-glucosidase	-
KJP78_RS18965 (NRS6183_18805)	mdxK	3589341..3591614 (-)	2274	WP_029725965.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=1156546 KJP78_RS18950 WP_003228214.1 3586336..3586929(+) (clpP) [Bacillus subtilis isolate NRS6183]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=1156546 KJP78_RS18950 WP_003228214.1 3586336..3586929(+) (clpP) [Bacillus subtilis isolate NRS6183]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
GGAAAAAGGCAAACGCTATGCACTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGTGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538