Detailed information NTG1154318

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: AD178_RS04815
• Genome accession: NZ_OX244288
• Coordinates: 937440..938090 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387347.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PT8105 isolate 2RLC4
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 932440..943090

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AD178_RS04785 (SAMEA1463109_00963)	-	932923..933138 (+)	216	WP_001232082.1	YozE family protein	-
AD178_RS04790 (SAMEA1463109_00964)	-	933224..934192 (+)	969	WP_000658183.1	PhoH family protein	-
AD178_RS04795 (SAMEA1463109_00965)	-	934385..934885 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
AD178_RS04800 (SAMEA1463109_00966)	-	934888..935214 (+)	327	Protein_948	TfoX/Sxy family protein	-
AD178_RS04805 (SAMEA1463109_00968)	ald	935515..936626 (-)	1112	Protein_949	alanine dehydrogenase	-
AD178_RS04810 (SAMEA1463109_00969)	-	936803..937372 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
AD178_RS04815 (SAMEA1463109_00970)	comEA/celA/cilE	937440..938090 (+)	651	WP_000387347.1	helix-hairpin-helix domain-containing protein	Machinery gene
AD178_RS04820 (SAMEA1463109_00971)	comEC/celB	938074..940314 (+)	2241	WP_000942417.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AD178_RS04825	-	940493..940681 (+)	189	WP_001809102.1	hypothetical protein	-
AD178_RS04830 (SAMEA1463109_00972)	-	940713..941300 (+)	588	WP_000933542.1	ABC transporter ATP-binding protein	-
AD178_RS04835 (SAMEA1463109_00973)	-	941304..942488 (+)	1185	WP_000655955.1	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23135.40 Da
• Isoelectric Point: 5.5415

>NTDB_id=1154318 AD178_RS04815 WP_000387347.1 937440..938090(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTGKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDYREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=1154318 AD178_RS04815 WP_000387347.1 937440..938090(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGGAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACTATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACCATAGAAAAACTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae Rx1	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae D39	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae R6	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	92.13	100	0.921
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	34.764	100	0.375
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366