Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   CKV85_RS08260 Genome accession   NZ_LT906454
Coordinates   1705750..1706457 (-) Length   235 a.a.
NCBI ID   WP_017769510.1    Uniprot ID   -
Organism   Streptococcus acidominimus strain NCTC11291     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1700750..1711457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV85_RS08245 (SAMEA4504048_01752) rnc 1702741..1703433 (-) 693 WP_095123261.1 ribonuclease III -
  CKV85_RS08250 (SAMEA4504048_01753) vicX 1703600..1704409 (-) 810 WP_017769512.1 MBL fold metallo-hydrolase Regulator
  CKV85_RS08255 (SAMEA4504048_01754) vicK 1704411..1705757 (-) 1347 WP_095123263.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CKV85_RS08260 (SAMEA4504048_01755) vicR 1705750..1706457 (-) 708 WP_017769510.1 response regulator YycF Regulator
  CKV85_RS08265 (SAMEA4504048_01756) - 1706688..1707470 (+) 783 WP_095123265.1 amino acid ABC transporter ATP-binding protein -
  CKV85_RS08270 (SAMEA4504048_01757) - 1707485..1708309 (+) 825 WP_017769508.1 transporter substrate-binding domain-containing protein -
  CKV85_RS08275 (SAMEA4504048_01758) - 1708561..1709256 (+) 696 WP_017769507.1 amino acid ABC transporter permease -
  CKV85_RS08280 (SAMEA4504048_01759) - 1709272..1709919 (+) 648 WP_017769506.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26832.70 Da        Isoelectric Point: 4.8027

>NTDB_id=1147494 CKV85_RS08260 WP_017769510.1 1705750..1706457(-) (vicR) [Streptococcus acidominimus strain NCTC11291]
MKTILVVDDEKPISDIIKFNLSKEGYTIVTAFDGHEAVQQFEDVKPDLVILDLMLPGIDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELLARVKAQLRRVETIESVAEESLQASSSEIEIGNLQIVPEAFIAKKNGEEVEL
THREFELLYHLAQHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIETTPSRPEYILTRRGVGYFMKAHD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1147494 CKV85_RS08260 WP_017769510.1 1705750..1706457(-) (vicR) [Streptococcus acidominimus strain NCTC11291]
ATGAAAACAATTCTTGTGGTTGATGATGAAAAACCCATCTCAGATATTATAAAATTCAATCTCAGTAAGGAAGGCTATAC
TATTGTAACTGCTTTTGACGGTCATGAGGCTGTTCAGCAGTTTGAAGATGTCAAGCCAGATTTAGTGATCTTGGACTTGA
TGTTACCAGGAATTGATGGCCTTGAAGTTGCTAAAGAAATTCGTAAAACGAGTCATACTCCGATTATCATGTTGTCTGCT
AAGGACTCTGAGTTTGATAAAGTTATCGGTTTAGAGATCGGGGCAGATGATTACATGACCAAACCTTTCTCAAATCGTGA
GCTTCTTGCACGCGTTAAAGCCCAGTTGCGTCGCGTAGAGACGATTGAAAGTGTTGCTGAGGAGTCTCTTCAAGCGTCGT
CATCTGAAATTGAAATTGGGAATTTACAGATTGTTCCTGAAGCCTTTATTGCTAAAAAGAATGGCGAAGAAGTGGAGTTG
ACACATCGTGAGTTTGAGTTGCTCTATCATTTGGCGCAACACATTGGACAGGTTATGACGCGCGAGCATTTGCTTGAGAC
GGTGTGGGGCTATGACTACTTCGGTGATGTCCGTACAGTTGATGTCACTATCCGTCGCTTGCGTGAAAAAATTGAGACCA
CACCAAGCCGTCCAGAATACATCCTAACTCGCCGTGGCGTAGGCTACTTTATGAAAGCTCATGACTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

79.149

100

0.791
  micA Streptococcus pneumoniae Cp1015

74.786

99.574

0.745
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.857

98.298

0.421
  covR Streptococcus salivarius strain HSISS4

41.88

99.574

0.417
  scnR Streptococcus mutans UA159

37.447

100

0.374

Multiple sequence alignment