Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   CKV85_RS08255 Genome accession   NZ_LT906454
Coordinates   1704411..1705757 (-) Length   448 a.a.
NCBI ID   WP_095123263.1    Uniprot ID   -
Organism   Streptococcus acidominimus strain NCTC11291     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1699411..1710757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV85_RS08245 (SAMEA4504048_01752) rnc 1702741..1703433 (-) 693 WP_095123261.1 ribonuclease III -
  CKV85_RS08250 (SAMEA4504048_01753) vicX 1703600..1704409 (-) 810 WP_017769512.1 MBL fold metallo-hydrolase Regulator
  CKV85_RS08255 (SAMEA4504048_01754) vicK 1704411..1705757 (-) 1347 WP_095123263.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CKV85_RS08260 (SAMEA4504048_01755) vicR 1705750..1706457 (-) 708 WP_017769510.1 response regulator YycF Regulator
  CKV85_RS08265 (SAMEA4504048_01756) - 1706688..1707470 (+) 783 WP_095123265.1 amino acid ABC transporter ATP-binding protein -
  CKV85_RS08270 (SAMEA4504048_01757) - 1707485..1708309 (+) 825 WP_017769508.1 transporter substrate-binding domain-containing protein -
  CKV85_RS08275 (SAMEA4504048_01758) - 1708561..1709256 (+) 696 WP_017769507.1 amino acid ABC transporter permease -
  CKV85_RS08280 (SAMEA4504048_01759) - 1709272..1709919 (+) 648 WP_017769506.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 51091.33 Da        Isoelectric Point: 4.7677

>NTDB_id=1147493 CKV85_RS08255 WP_095123263.1 1704411..1705757(-) (vicK) [Streptococcus acidominimus strain NCTC11291]
MTDNLIFTFRDLIIAGLMSVLVLIFVFLIVREALNGKRTQLLTDQVRDLISGEYAINQVTRGSSEIRTLAQHLNDLSEVF
RLTHENLEQEKNRLSSILSYMSDGVLATDRRGNIIMINEMARQQLNLPEAGDVQLNIMTILEETSYTYHDLITKTPEVTL
NRVDEFGEFTVLRINFALIKRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKESV
APGFIKVSLDETNRMMRMITDLLSLSRIDNDKSHIEVELTNFTAFITYILNRFDQIKLQNTQAGKSYEIIRNYPLVPIWI
EIDNDKMTQVIDNIINNAIKYSPDGGEIIVSMRTTETQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGSGLGL
SIAKEIIKQHNGFIWAKSDYGKGSTFTIVLPYEKNILEVDEEWEESDN

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=1147493 CKV85_RS08255 WP_095123263.1 1704411..1705757(-) (vicK) [Streptococcus acidominimus strain NCTC11291]
ATGACTGATAACCTTATATTTACATTTCGCGATCTGATTATTGCGGGACTGATGTCTGTATTAGTCCTGATTTTTGTTTT
TTTGATTGTCCGTGAAGCCTTAAATGGCAAACGTACCCAGTTGCTCACTGATCAGGTTCGTGATCTCATTTCTGGTGAGT
ATGCTATTAATCAAGTAACCAGAGGCTCATCTGAAATTCGAACCTTGGCCCAACATCTGAATGATTTGTCAGAGGTCTTT
CGTCTTACTCATGAAAATCTAGAGCAAGAAAAGAACAGGCTTTCCAGCATCCTCTCCTATATGAGTGATGGTGTCTTGGC
TACTGATCGCAGGGGTAACATCATTATGATTAATGAGATGGCCCGGCAGCAGCTCAATTTACCAGAAGCGGGTGATGTTC
AGTTGAATATCATGACTATCTTAGAAGAGACATCCTATACTTATCATGATTTGATTACAAAAACACCAGAGGTGACCCTA
AATCGCGTGGATGAATTTGGGGAATTTACCGTTTTAAGGATTAATTTTGCCCTAATCAAAAGAGAAAGTGGTTTTATTTC
AGGTCTGGTAGCCGTTTTACATGATACAACGGAACAGGAAAAAGAAGAACGCGAACGCCGTCTCTTTGTTTCGAATGTGA
GTCATGAATTGAGAACGCCCTTGACCTCCGTAAAGTCTTATCTTGAAGCGCTTGATGAGGGGGCTTTAAAGGAGTCCGTG
GCTCCGGGATTTATCAAAGTATCACTTGACGAAACCAATCGCATGATGCGTATGATCACAGACCTCTTGTCGCTATCAAG
GATTGATAATGACAAGAGCCACATTGAAGTTGAGTTGACTAACTTTACAGCCTTTATTACCTATATCTTGAACCGTTTTG
ATCAAATCAAACTTCAAAACACGCAGGCGGGGAAATCCTACGAAATTATCCGCAACTATCCACTGGTTCCGATTTGGATT
GAGATTGATAATGATAAGATGACCCAGGTTATTGATAACATCATTAATAATGCGATTAAGTATTCACCAGATGGTGGTGA
AATCATCGTTAGCATGCGGACGACAGAAACGCAGTTGATTATCTCAATTTCTGACCAAGGTTTAGGTATTCCTAAAAAAG
ATCTGCCATTGATCTTTGATCGTTTTTATCGGGTGGATAAGGCCAGAAGTCGGGCACAGGGTGGTTCGGGACTTGGCTTG
TCGATTGCCAAAGAAATTATTAAACAACATAATGGTTTTATTTGGGCTAAAAGTGATTATGGCAAAGGGTCAACCTTTAC
CATCGTATTGCCGTATGAGAAAAATATTCTAGAAGTTGATGAAGAGTGGGAGGAGTCAGACAACTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(323-433)

His Kinase A (phospho-acceptor) domain (HisKA)

(206-270)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

72.019

91.741

0.661
  micB Streptococcus pneumoniae Cp1015

66.589

96.205

0.641

Multiple sequence alignment