Detailed information NTG1147131

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: CKV83_RS04515
• Genome accession: NZ_LT906439
• Coordinates: 975063..975653 (-)
• Length: 196 a.a.
• NCBI ID: WP_018372809.1
• Uniprot ID: A0A239STF0
• Organism: Streptococcus merionis strain NCTC13788
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 970063..980653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV83_RS04490 (SAMEA4412692_00900)	-	970180..970944 (-)	765	WP_018372804.1	ABC transporter ATP-binding protein	-
CKV83_RS04495 (SAMEA4412692_00901)	-	970945..971892 (-)	948	WP_018372805.1	branched-chain amino acid ABC transporter permease	-
CKV83_RS04500 (SAMEA4412692_00902)	-	971894..972763 (-)	870	WP_018372806.1	branched-chain amino acid ABC transporter permease	-
CKV83_RS04505 (SAMEA4412692_00903)	-	973060..974256 (-)	1197	WP_018372807.1	ABC transporter substrate-binding protein	-
CKV83_RS04510 (SAMEA4412692_00904)	-	974361..974639 (-)	279	WP_018372808.1	DUF2129 domain-containing protein	-
CKV83_RS04515 (SAMEA4412692_00905)	clpP	975063..975653 (-)	591	WP_018372809.1	ATP-dependent Clp protease proteolytic subunit	Regulator
CKV83_RS04520 (SAMEA4412692_00906)	-	976105..977331 (-)	1227	WP_282705045.1	lipopolysaccharide assembly protein LapB	-
CKV83_RS04525 (SAMEA4412692_00907)	-	977346..978479 (-)	1134	WP_018372811.1	AI-2E family transporter	-
CKV83_RS04530 (SAMEA4412692_00908)	-	978774..979790 (+)	1017	WP_018372812.1	lactonase family protein	-
CKV83_RS04535 (SAMEA4412692_00909)	-	979833..980024 (+)	192	WP_018372813.1	hypothetical protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21568.84 Da
• Isoelectric Point: 5.3086

>NTDB_id=1147131 CKV83_RS04515 WP_018372809.1 975063..975653(-) (clpP) [Streptococcus merionis strain NCTC13788]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINSPGGSVSAGLAIVDTMN
FIKSDVQTIVMGVAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTAAGTQQTDMAIVAERLLKTRNRLEKILSENSGK
SVKQIHKDAERDFWMDAKETLAYGFIDAIMETSDLK

Nucleotide

• Length: 591 bp

>NTDB_id=1147131 CKV83_RS04515 WP_018372809.1 975063..975653(-) (clpP) [Streptococcus merionis strain NCTC13788]
ATGATACCAGTAGTTATTGAACAAACTAGCCGTGGCGAACGTTCTTATGATATTTACTCCCGCCTGCTCAAAGATCGCAT
TATTATGCTGACAGGTCCAGTTGAAGACAATATGGCAAACTCTATTATTGCCCAATTGCTTTTCCTTGATGCTCAGGATA
ATACGAAAGATATCTACCTTTACATCAACTCACCAGGTGGCTCTGTATCAGCTGGCCTTGCTATCGTCGATACTATGAAT
TTCATCAAATCTGACGTGCAAACCATTGTTATGGGGGTAGCTGCTTCTATGGGAACAATCATCGCATCATCAGGCGCCAA
GGGCAAGCGTTTCATGTTACCAAACGCTGAATACCTCATTCATCAGCCAATGGGCGGAACAGCAGCAGGAACACAGCAGA
CGGATATGGCTATTGTAGCGGAACGCCTACTAAAAACCCGTAACCGCTTGGAGAAGATTTTGTCTGAGAACTCTGGCAAG
TCTGTTAAGCAAATCCATAAAGATGCTGAGCGCGATTTCTGGATGGATGCTAAAGAAACGTTGGCATACGGCTTTATTGA
TGCCATCATGGAAACCTCAGATCTTAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A239STF0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	91.327	100	0.913
clpP	Streptococcus pyogenes JRS4	87.245	100	0.872
clpP	Streptococcus pyogenes MGAS315	87.245	100	0.872
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Streptococcus thermophilus LMD-9	84.694	100	0.847
clpP	Streptococcus pneumoniae D39	84.694	100	0.847
clpP	Streptococcus pneumoniae Rx1	84.694	100	0.847
clpP	Streptococcus pneumoniae R6	84.694	100	0.847
clpP	Streptococcus pneumoniae TIGR4	84.694	100	0.847
clpP	Streptococcus thermophilus LMG 18311	84.694	100	0.847
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.067	98.469	0.582
clpP	Bacillus subtilis subsp. subtilis str. 168	56.853	100	0.571